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73 Cards in this Set

  • Front
  • Back
5 categories of abnormal uterine bleeding
1. Amenorrhea
2. Ovulatory bleeding
3. Anovulatory bleeding
4. Post-coital bleeding
5. Post-menopausal bleeding
failure of menarche by age 14 if no secondary sex characteristics OR by 16 if secondary sex characteristics are present

most likely cause?
anatomic disorder

primary amenorrhea
absence of menstruation for 6 months

cause?
chronic anovulation

secondary amenorrhea
amenorrhea

causes?
• Anatomic – present with primary amenorrhea
• Ovarian failure
• Chronic anovulation – present with secondary amenorrhea
• Also evaluate women who experience amenorrhea if they have no breast development by age 14 or if any sexual ambiguity or virilization is present
30 yo female
amenorrhea

most likely cause?
pregnancy

rule of pregnancy in women of reproductive age
cyclic menstrual bleeding that is excessive in time (>7days) or amount (>80mL)

cause?
Anatomic - leimyoma, uterine polyps

Chronic anovulation like endometrial hyperplasia due to unopposed estrogen secretion


menorrhagia
unpredictable bleeding of variable duration and amont
Anovulatory Bleeding
bleeding at intervals longer than 35 days
Oligomenorrhea
prolonged uterine bleeding that is also irregular
Menometrorrhagia
Post-coital bleeding

sign of?
cervical cancer

dd:
cervical erosion
• History of menometrorrhagia since menarche
Coagulopathy
what do you use to determine presence of ovulatory or anovulatory cycles
• Basal body temperature graphs
• Enlarged, irregular uterus
leiomyomas
• Symmetrically enlarged uterus
adenomyosis or endometrial carcinoma
atrophic and inflammatory
vulvar and vaginal lesions, cervical polyps, and invasive lesions of cervical carcinoma
• Velvety, friable erythematous lesion on ectocervix
pregnancy
what do you look for on a pap smear?
asymptomatic intraepithelial lesions of the cervix
• Invasive ectocervical lesions
• Endocervical lesions
ways of evaluating endometrial lining
Endometrial Biopsy,
Pelvic Ultrasound
Hysteroscopy
how to assess for complications in pregnancy and trophoblastic disease
• B-hCG
which test to evaluate adnexial masses
• Pelvic ultrasound and laproscopy
test to determine cause of post-coital bleeding
• Colpscopy
effect of hypothyroidism on bleeding?
increase uterine bleeding
effect of liver disease on estrogen

result?
interferes with estrogen metabolism → bleeding
• Blood dyscrasias and coagulation abnormalities

cause?
o Check if patient is receiving anticoagulants or adrenal steroids
Bleeding due to non-gynecological reasons (4)
1. hypothyroidism
2. liver disease
3. anticoagulants/steroids
4. extreme weight loss
abnormal uterine bleeding
vulva and vagina
atrophic vulvitis/vaginitis
trauma
infection
cancer
Cervix pathologies
erosion
polyp
cancer
pedunculated myoma (fibroids)
abnormal uterine bleeding
uterus
endometritis
hyperplasia
cancer
polyp
adenomyosis
submucous myoma
oral contraceptives
perforation due to IUDs
pregnancy
Asherman
Mullerian agenesis
abnormal uterine bleeding
uterine/fallopian tubes
tubal pregnancy
abnormal uterine bleeding
ovaries
estrogen-producing tumor
malignancies
ovarian cysts
benefit of myomectomy
retains childbearing ability
abnormal uterine bleeding

protocol?
check for:
- pregnancy
- contraceptives
- IUDs
- hormones

if no pathology, cancer, hemorrhage:
- treat w/ hormones
complication of vigorous curettage
previous uterine surgery
severe infection
TB

histology?
scarring (synechiae)
destruction of basal endometrium (no proliferation & sloughing during menses)

Asherman syndrome
amenorrhea
recurrent miscarriage
uterine scarring

tx?
Hysterosalpingography
Hysteroscopic lysis of adhesions
- allows precise division of bands and documentation

Asherman's syndrome
outflow obstruction or lack of endometrium
Mullerian agenesis
diff b/w complete & partial mullerian agenesis
complete: no mullerian structures at all

partial: rudimentary bulbs w/ active endometrium
amenorrhea
vaginal dimple
complete mullerian agenesis
amenorrhea
cyclic abdominal pain
partial mullerian agenesis
(functional endometrium)
outflow obstruction
vaginal dimple

tx?
vaginal dilation
surgical neovagina

Mayer-Rokitansky-Kuster-Hauser syndrome
(Complete Mullerian Agenesis)
african american female
menorrhagia
enlarged uterus on pelvic exam

tx?
• Hysterectomy
• Myomectomy
• Uterine artery embolization
• Magnetic resonance-guided focused ultrasound surgery

Uterine leimyoma
enlarges in pregnancy
regress after menopause
uterine leimyoma
what test do you use to see if a uterine leimyoma is subserosal, submucosa, intramural, or pedicle?
transvagina sonography
45 yo female
multiple kids
symmetric globular uterine enlargement
menorrhagia
passage of large clots
increased dysmenorrhea

histology?
ectopic rests of endometrium located deep in myometrium

adenomyosis
ectopic rests of endometrium located deep in myometrium

tx?
NSAIDs
hormonal contraception
endometrial ablation

adenomyosis
Cytp450 aromatase is associated with this
adenomyosis
• Gene translocation on chromosome 6 and 12
polyps
• Estrogen and progesterone
• HTN, obesity, tamoxifen

histology?
soft, fleshy mass of endometrial glands and stroma

polyps
mass extends out of cervical os
menorrhagia
metrorrhagia
post-coital bleeding
endocervical polyps
bleeding, but fetus is still alive
threatened abortion
passage of some fetal or placental tissue
incomplete abortion
placenta inserts over the cervical os
placenta previa
placenta pulls away from the uterus
placental abruption
colicky pain w/o bleeding in pregnancy
abortion
adnexial mass when palpated (corpus luteum felt)
no bleeding
threatened abortion
unilateral pain in lower abdominal quadrant
no bleeding
Uterus tender
distended tube


syncope...what happened?
tube rupture -> acute intense pain -> syncope

ectopic pregnancy
acute intense pain -> syncope -> prompt recovery -> bleeding continues -> less acute abdominal pain

where does the pain get referred to? why?
shoulder after it reaches diaphragm when patient lies down from dizziness

ectopic pregnancy
ectopic pregnancy

besides the intense pain, what else causes syncope
hemoperitoneum = low EABV
positive pregnancy test
empty uterus
adnexal mass by vaginal sonography
ectopic pregnancy
causes of post-menopausal bleeding
exogenous hormones
tumors
vaginal atrophy/lesions
post-menopausal bleeding

assume what?
could also be what?
endometrial cancer -> sonography, biopsy

endometrial hyperplasia/estrogen secreting ovarian tumor
post-menopausal bleeding
lower reproductive tract

what will exam show?
tx?
vaginal atrophy

tissue w/ ecchymosis (bruise), tear

tx w/ systemic estrogen therapy
post-menopausal bleeding
white area and cracking of skin

cytology?
immature epithelial cells
inflammation

vulvar dystrophy
no breast development by age 14
primary amenorrhea
sexual ambiguity

what do you do?
evaluate for primary amenorrhea
chronic anovulation with estrogen present

type of hypthalamic function disorder?
secondary
chronic anovulation with estrogen absent

type of hypothalamic function disorder
primary
kallman's syndrome is assoc w/ which type of chronic anovulation

(failure of GnRH neurons to migrate to right spot in hypothalamus)
estrogen absent
enlarged, irregular uterus
leimyoma
most common indication for hysterecomy
leimyoma
early pregnancy complications
threatened abortion
trophoblastic disease
late pregnancy complications
placenta previa
placental abruption
uterine rupture
inappropriately rising B-hCG
no gestational sac in uterus
complex adnexal mass
ectopic pregnancy
abnormal bleeding in a female child
trauma
foreign body
vagina tumor (sarcoma)
precocious puberty
prolapsed urethra