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9 Cards in this Set
- Front
- Back
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Description |
Platelet aggregation inhibitor, analgesic and anti-inflammatory agent |
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Class |
Cardiac |
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Indications |
Chest pain, suspected AMI, Unstable angina, mild to moderate pain or fever |
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Mechanism of action |
Inhibits cyclooxygenase 2 enzyme (COXX2) leading to reduced synthesis of the platelet aggregation factor thromboxxane A2 (TXXA2) and prostaglandins |
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Pharmacokinetics |
Onset: 2-10 minutes - Peak: 3-6 hours - Duration: upto 24 hours |
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Contraindications |
Hypersensitivity to salicylates, active bleeding, suspected severe bleeding tendancy |
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Adverse effects |
Heartburn, gastritis, nausea, vomiting, wheezing and allergic reaction |
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Precaution |
Pregnancy |
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Drug-drug interactions |
Decreased effects with antacids and steroids , Increased effects with anticoagulants, insulin, oral hypoglycemics, fibrinolytic agents |
