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27 Cards in this Set
- Front
- Back
- 3rd side (hint)
Eukaryotic proofreading DNA polymerases |
Delta |
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This DNA polymerase also has 5'-3' exonuclease activity |
Epsilon |
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This DNA polymerse has primase activity. |
alpha |
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These DNA polymerases are responsible for Leading/lagging strand synthesis and repair |
Alpha |
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This polymerase is only involved in mitochondrial DNA replication |
gamma |
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This polymerase is only involved in repair |
Beta |
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All Eukaryotic DNA polymerases are found in the nucleas except: |
gamma |
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_______ binds with helicase, which unwinds the dsDNA molecule |
Replicating factor A |
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Primase activity of pol ___ starts up the synthesis of the leading strand |
alpha |
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Replicating factor C |
Replace pol alpha in order to increase processivity |
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Every okazaki fragment requires the switching between pol _ and _ |
Pol alpha followed by delta |
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Composed of both RNA and protein |
Telomerase |
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The RNA will base pair with the 3' end of DNA |
the 3' overhang |
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Telomerase shifts by _____ nucleotides and is positioned to synthesize another repeat. |
six |
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Three cells with high telomerase activity |
1. Stem cells |
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- Small body size |
Adult progeria (Werner's syndrome: WS) |
Mutation in the WRN gene (chromosome 8) |
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1. DNA polymerase activity |
Properties of reverse transcriptase |
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Proteases |
mature retroviral particle |
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1. Nucleotide analogs. |
Inhibitors of replication |
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1. Conversion of nucleoside to a nucleotide |
Nucleotide analog mechanism. |
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1. Binds to and inhibits DNA gyrase |
Mechanism for inhibitors that bind to enzymes involved with replication |
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The insertion of a molecule between adjacent base-pairs in a DNA molecule |
Intercalation |
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1. Increases the spacing of the adjacent base-pairs at the site of intercalation |
Mechanism of inhibitors that bind to or modify DNA |
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Alters B form of DNA |
Ethiidium bromide |
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Name the transcription factor: |
TFIIH |
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Protein containing RNA molecule. |
RNase P |
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Deamidation of adenine yields.... |
hypoxanthine |
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