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56 Cards in this Set
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Endocrine system |
A system of ductless glands that secrete chemical messages or hormones into bloodstreams that carry to specific target |
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Basic endocrine glands (8) |
Pituitary glands Thyroid Parathyroid Adrenal gland Pineal gland Thymus Portions of : Pancreas Gonads |
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Pituitary gland location |
Brain |
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Posterior pituitary |
A.k.a. Neurohypophysis Back half |
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Anterior pituitary |
A.k.a. Adenhypophysis Front half |
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Posterior pituitary gland |
Hypothalamus |
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Hypothalamus |
Another part of brain Deep inside Produces hormones that control, body temperature, heart rate and hunger |
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Oxytocin |
Made by hypothalamus and pituitary releases A hormone that controls contraction during childbirth Uterus is induced with Pitocin, which is synthetic oxytocin |
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ADH |
Made by hypothalamus the pituitary releases Antidiuretic hormone H2O regulator Kidneys, clean, blood recycle compounds, And water Caffeine inhibits ADH makes, you pee, pulls out water |
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Anterior pituitary glands(6) |
FSH LH TSH ACTH Prolactin GH or HGH |
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FSH |
Follicle-stimulating hormone Anterior pituitary Target: ovaries and testes And women, it promotes development of egg and in men it promotes development of sperm |
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LH |
Luteinizing Hormone Promote : ovulation Testosterone Target : testes Fallopian tube |
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Birth control |
Tricks body into believing pregnancy by causing the levels of FSH and LH to go down |
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TSH |
Thyroid stimulating hormone Target : thyroid Promotes : the release of thyroid hormones, and normal body development |
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ACTH |
Adrenocorticotropic hormone Biological clock Circadian rhythm normal routine A lot of stress lot of ACTH Stress hormone |
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Prolactin |
Lact promotes development of breast milk for women, and not major for men Target mammory gland |
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GH or HGH |
Human growth hormone Promote, skeletal muscle and bone growth Banned as a PED Endurance athletes take to recover |
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Thyroid |
Largest pure endocrine gland Location : neck Hypo / hyper thyroidism Hyper destroys or gets rid of Take hormones Iodine equals no goiter |
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T3 T4- thyroxine TH |
Calcitonin lowers calcium levels Lactose intolerant get calcium from orange juice Regulate blood pressure and metabolism |
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Endocrinologist |
Study hormones |
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Parathyroid |
Within thyroid Chief cells destroy, or digest bones, osteoclasts On top of thyroid, go to bone osteoclast |
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PTH |
Parathyroid hormone Increase calcium levels Use later when in need of calcium Oxyoclast stem there for a reason |
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Adrenal gland |
Location : above kidneys Two regions : adrenal medulla Adrenal cortex |
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Adrenal cortex |
Center of gland Corticosteroids and corticohormones |
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Mineralocorticoids |
Steroid/lipid Banned Aldosterone- NA build muscle mass Regulate minerals and inorganic compounds |
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Glucocorticoids |
Steroid/lipid Cortizone – anti-inflammatory, reduce swelling Helps regulate glucose and bloodstream and regulate amount of blood in your body |
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Gonadocorticoids |
Adrenal cortex Man: estrogen Women: testosterone Second sex characteristics Puberty |
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Adrenal medulla |
Surround cortex Secrete, lots of hormones |
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Epinephrine |
Increase heart rate Homeostasis Adrenaline, EpiPen Heart rate increase to flush out of system Sick to stomach, pee yourself Fight or flight |
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Norepinephrine |
Counteract epinephrine |
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Pancreas |
Attached a small intestine Mixed organ Islets of Langerhans Diabetes |
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Islets of Langerhans |
Scatter pancreas 1. Alpha cells 2. Beta cells |
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Alpha cells |
Release will need to increase sugar in the blood stream Target : liver Help regulate sugar/carbohydrates Glucagon - glycogen Carbohydrates in bloodstream, leftover transport to liver, stored as glycogen |
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Beta cells |
More beta than alpha Insulin, sugar Released to mediate/ remove sugar into all cells for cellular energy Hypoglycemia equals low sugar and hyperglycemia equals high sugar |
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Type one and two diabetes |
Type one – juvenile Can’t/not enough/rejecting So insulin-dependent Type two – mature onset Later in life, mostly overweight |
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Diabetes symptoms |
Poly equals many/excessive 1) polyphagia – excessive hunger 2) polyuria – excessive urination 3) polydipsia – excessive thirst 70 ~ 120 ppm 1950 – diabetes treatment grind up cow pancreas now bacteria made |
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Physiology of diabetes |
Cellular metabolism: 1) no sugar – use proteins, and fat Ends up in kidneys and pees out insulin/sugar Can’t make sugar than use proteins/fat 2) ketones – organic acid Lower blood pH 7.2–7.3 3) ketoacidosis- coma, could die |
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Keto diet |
Mimics, diabetes Protein and fat to burn fat, lack sugar Can only do for about two weeks must back off before keto acidosis occurs very dangerous |
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Pineal gland |
Location: brain, small portion, deep inside |
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Melatonin |
Pineal Help regulate sleep cycle Older you get less you release Why your grandparents get up so early |
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Importance of melatonin to bears |
HIBERNATION Winter solstice versus summer solstice Melatonin is not secreted with UV light Bears pick up, on less uv which secretes more melatonin UV rays penetrate cave, so bears secrete, less melatonin, and come out of hibernation |
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Thymus |
The older you get the more it shrinks Prime. At puberty |
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Thymoprotein |
WBC/immune system T – lymphocytes – tells pituitary gland to release |
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Gonads |
1) testes 2) ovary |
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Testes |
Testosterone Production of sperm, making muscle mass, red blood cell production, bone mass, overall fitness |
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Ovary |
Estrogen – second sex characteristics Progesterone – menstrual cycle Osteoporosis/bone mass Endometrin – lining of uterus, egg, released and prepares for pregnancy Endometriosis – inflamed endometrium, prevent pregnancy |
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Hormone |
Chemical signal that is secreted into blood to a target(s) |
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Types of hormones |
1) amino acid base 2) steroid base 3) Eicosanoids |
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Amino acid base |
Protein Protein target Receptors outside the cell target Receptors are signals for something to bind to |
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Steroid base |
Lipid Corticosteroids Gonadal hormones Only two glands |
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Why are steroid shots and not pills? |
Lipids are liquid and not soluble in water |
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Eicosanoids |
Lipids Secreted by cells and not glands Local effect on cells in that area Biologically, active, lipid Do not enter bloodstream |
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Types of Eicosanoids |
Leukotrienes Prostaglandins |
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Leukotrienes |
Eicosanoids Combines with cells and nose and causes to release reaction to sinus Allergic reactions Histamine reaction Histamine throat reaction |
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Prostaglandins |
Chemical released by cell Blood clot Induce pain Uterine contractions |
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Mechanisms of action/effects or changes in target cells |
Can have one or many Cell membrane permeability Stimulate protein/enzyme production Activate or deactivate enzymes Induced secretions Stimulate mitosis |