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56 Cards in this Set

  • Front
  • Back

Endocrine system

A system of ductless glands that secrete chemical messages or hormones into bloodstreams that carry to specific target

Basic endocrine glands (8)

Pituitary glands


Thyroid


Parathyroid


Adrenal gland


Pineal gland


Thymus


Portions of :


Pancreas


Gonads

Pituitary gland location

Brain

Posterior pituitary

A.k.a. Neurohypophysis


Back half

Anterior pituitary

A.k.a. Adenhypophysis


Front half

Posterior pituitary gland

Hypothalamus

Hypothalamus

Another part of brain


Deep inside


Produces hormones that control, body temperature, heart rate and hunger

Oxytocin

Made by hypothalamus and pituitary releases


A hormone that controls contraction during childbirth


Uterus is induced with Pitocin, which is synthetic oxytocin

ADH

Made by hypothalamus the pituitary releases


Antidiuretic hormone


H2O regulator


Kidneys, clean, blood recycle compounds, And water


Caffeine inhibits ADH makes, you pee, pulls out water

Anterior pituitary glands(6)

FSH


LH


TSH


ACTH


Prolactin


GH or HGH

FSH

Follicle-stimulating hormone


Anterior pituitary


Target: ovaries and testes


And women, it promotes development of egg and in men it promotes development of sperm

LH

Luteinizing Hormone


Promote : ovulation


Testosterone


Target : testes


Fallopian tube

Birth control

Tricks body into believing pregnancy by causing the levels of FSH and LH to go down

TSH

Thyroid stimulating hormone


Target : thyroid


Promotes : the release of thyroid hormones, and normal body development

ACTH

Adrenocorticotropic hormone


Biological clock


Circadian rhythm normal routine


A lot of stress lot of ACTH


Stress hormone

Prolactin

Lact


promotes development of breast milk for women, and not major for men


Target mammory gland

GH or HGH

Human growth hormone


Promote, skeletal muscle and bone growth


Banned as a PED


Endurance athletes take to recover

Thyroid

Largest pure endocrine gland


Location : neck


Hypo / hyper thyroidism


Hyper destroys or gets rid of


Take hormones


Iodine equals no goiter

T3 T4- thyroxine TH

Calcitonin lowers calcium levels


Lactose intolerant get calcium from orange juice


Regulate blood pressure and metabolism

Endocrinologist

Study hormones

Parathyroid

Within thyroid


Chief cells destroy, or digest bones, osteoclasts


On top of thyroid, go to bone osteoclast

PTH

Parathyroid hormone


Increase calcium levels


Use later when in need of calcium


Oxyoclast stem there for a reason

Adrenal gland

Location : above kidneys


Two regions : adrenal medulla


Adrenal cortex

Adrenal cortex

Center of gland


Corticosteroids and corticohormones

Mineralocorticoids

Steroid/lipid


Banned


Aldosterone- NA build muscle mass


Regulate minerals and inorganic compounds

Glucocorticoids

Steroid/lipid


Cortizone anti-inflammatory, reduce swelling


Helps regulate glucose and bloodstream and regulate amount of blood in your body

Gonadocorticoids

Adrenal cortex


Man: estrogen


Women: testosterone


Second sex characteristics


Puberty

Adrenal medulla

Surround cortex


Secrete, lots of hormones

Epinephrine

Increase heart rate


Homeostasis


Adrenaline, EpiPen


Heart rate increase to flush out of system


Sick to stomach, pee yourself


Fight or flight

Norepinephrine

Counteract epinephrine

Pancreas

Attached a small intestine


Mixed organ


Islets of Langerhans


Diabetes

Islets of Langerhans

Scatter pancreas


1. Alpha cells


2. Beta cells

Alpha cells

Release will need to increase sugar in the blood stream


Target : liver


Help regulate sugar/carbohydrates


Glucagon - glycogen


Carbohydrates in bloodstream, leftover transport to liver, stored as glycogen

Beta cells

More beta than alpha


Insulin, sugar


Released to mediate/ remove sugar into all cells for cellular energy


Hypoglycemia equals low sugar and hyperglycemia equals high sugar

Type one and two diabetes

Type one – juvenile


Can’t/not enough/rejecting


So insulin-dependent


Type two mature onset


Later in life, mostly overweight

Diabetes symptoms

Poly equals many/excessive


1) polyphagia – excessive hunger


2) polyuria – excessive urination


3) polydipsia excessive thirst


70 ~ 120 ppm


1950 – diabetes treatment grind up cow pancreas now bacteria made

Physiology of diabetes

Cellular metabolism:


1) no sugar – use proteins, and fat


Ends up in kidneys and pees out insulin/sugar


Can’t make sugar than use proteins/fat


2) ketones – organic acid


Lower blood pH 7.2–7.3


3) ketoacidosis- coma, could die

Keto diet

Mimics, diabetes


Protein and fat to burn fat, lack sugar


Can only do for about two weeks must back off before keto acidosis occurs very dangerous

Pineal gland

Location: brain, small portion, deep inside

Melatonin

Pineal


Help regulate sleep cycle


Older you get less you release


Why your grandparents get up so early

Importance of melatonin to bears

HIBERNATION


Winter solstice versus summer solstice


Melatonin is not secreted with UV light


Bears pick up, on less uv which secretes more melatonin


UV rays penetrate cave, so bears secrete, less melatonin, and come out of hibernation

Thymus

The older you get the more it shrinks


Prime. At puberty

Thymoprotein

WBC/immune system


T – lymphocytes – tells pituitary gland to release

Gonads

1) testes


2) ovary

Testes

Testosterone


Production of sperm, making muscle mass, red blood cell production, bone mass, overall fitness

Ovary

Estrogen second sex characteristics


Progesterone menstrual cycle


Osteoporosis/bone mass


Endometrin – lining of uterus, egg, released and prepares for pregnancy


Endometriosis – inflamed endometrium, prevent pregnancy

Hormone

Chemical signal that is secreted into blood to a target(s)

Types of hormones

1) amino acid base


2) steroid base


3) Eicosanoids

Amino acid base

Protein


Protein target


Receptors outside the cell target


Receptors are signals for something to bind to

Steroid base

Lipid


Corticosteroids


Gonadal hormones


Only two glands

Why are steroid shots and not pills?

Lipids are liquid and not soluble in water

Eicosanoids

Lipids


Secreted by cells and not glands


Local effect on cells in that area


Biologically, active, lipid


Do not enter bloodstream

Types of Eicosanoids

Leukotrienes


Prostaglandins

Leukotrienes

Eicosanoids


Combines with cells and nose and causes to release reaction to sinus


Allergic reactions


Histamine reaction


Histamine throat reaction

Prostaglandins

Chemical released by cell


Blood clot


Induce pain


Uterine contractions

Mechanisms of action/effects or changes in target cells

Can have one or many


Cell membrane permeability


Stimulate protein/enzyme production


Activate or deactivate enzymes


Induced secretions


Stimulate mitosis