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15 Cards in this Set
- Front
- Back
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Gastritis |
Stomach (lining) inflammation |
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Gastric glands |
Contain: -parietal cells -chief cells -mucous cells |
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parietal cells |
=oxyntic cells -hydrochloric acid producing (as separate ions) |
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chief cells
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produce an enzyme precursor called pepsinogen |
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mucous cells |
produce the protective mucus layer |
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histamine receptors |
greates impact on acid production |
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enterochromaffin-like cells |
specialized cells in stomach that secrete H2 receptors (stimulated by histamine) Produce histamine |
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gastrin |
locallly produced hormone produced by G cells in distal part of the stomach and proximal part of duodenum hormone normally released from stomach wall in response to proteins signals relaxation of the stomach wall |
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mucins |
complex molecules produced by the mucus-producing cells in the gastric glands main constituent of the mucous coating |
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bicarbonate ion |
also secreted and added to the mucous coat mkaing it more alkaline neutralize hydrochloric acid |
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prostaglandins |
-stimulates mucus production -inhibits acid production by parietal cells |
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antacids |
decrease stomach acidity by -chemically combining with HCl -decreasing acid production |
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nonsystemic antacids |
given by mouth not absorbed, instead directly neutralize acid molecules in stomach or rumen rare side effets |
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systemic antacids |
must be absrobed, circulate, and attach to receptors of the cells of the stomach to produce their effect |
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proton pump inhibitor |
acid pump omeprazole (systemic antacid) inhibits pump that normally transports hydrogen ions into the stomach lumen |
