Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
43 Cards in this Set
- Front
- Back
T1
|
2cm or less
|
|
T1mi
|
1mm or less (microinvasive)
|
|
T1a
|
>0.1 to 0.5cm
|
|
T1b
|
>0.5 to 1cm
|
|
T1c
|
>1cm to 2cm
|
|
T2
|
>2cm to 5cm
|
|
T3
|
> 5cm
|
|
T4
|
Chest wall/skin
|
|
T4a
|
chest wall (not including pectoralis muscle)
|
|
T4b
|
skin edema (peau d'orange), ulceration, or satellite skin nodules
|
|
T4c
|
both 4a and 4b
|
|
T4d
|
inflammatory carcinoma
|
|
cN1
|
movable ipsilateral axillary lymph nodes
|
|
pN1mi
|
micromets (> 0.2mm but <= 2.0mm)
|
|
pN1a
|
1-3 axillary lymph nodes (at least 1 >2.0mm)
|
|
pN1b
|
Metastases in IM nodes (micrometastases, or macrometastases detected by SLN biopsy but not clinically detected)
|
|
pN1c
|
1-3 axillary lymph nodes and metastases in IM nodes (micrometastases, or macromets detected by SLN but not clinically detected)
|
|
cN2a
|
Ipsilateral axillary lymph nodes fixed or matted
|
|
pN2a
|
4-9 axillary lymph nodes (at least 1 > 2.0 mm)
|
|
cN2b
|
Clinically detected internal mammary nodes in the absence of axillary lymph node metastases
|
|
pN2b
|
Metastases in clinically detected IM nodes in the absence of axillary lymph nodes
|
|
cN3a
|
Infraclavicular lymph nodes (level III)
|
|
pN3a
|
10 or more axillary lymph nodes (at least 1 > 2.0 mm); or infraclavicular (level III) lymph nodes
|
|
cN3b
|
Clinically apparent internal mammary nodes with axillary lymph node involvement
|
|
pN3b
|
Metastases in clinically detected IM nodes in the presence of positive axillary nodes; or microscopic IM nodes and more than 3 axillary lymph nodes
|
|
cN3c
|
Supraclavicular lymph nodes
|
|
pN3c
|
Supraclavicular lymph nodes
|
|
"A" nodes are ...
|
"A"xillary
|
|
"B" nodes are ...
|
internal "B"reast nodes (e.g. IMNs)
|
|
"C" nodes are ...
|
supra"C"lavicular excludes N1 subtype
|
|
Stage IA
|
T1N0
|
|
Stage IB
|
T0-1, N1mi
|
|
Stage IIA
|
T0-1 N1 or T2N0
|
|
Stage IIB
|
T2 N1 or T3 N0
|
|
Stage IIIA
|
T3 N1 or T0-3 N2
|
|
Stage IIIB
|
T4 N0-2
|
|
Stage IIIC
|
N3
|
|
Stage IV
|
M1
|
|
changes from 6th edition:
|
- T1mic changed to T1mi to indicate microscopic disease
- Clarification of wording of "not clinically detected" and "clinically detected" internal mammary nodes. *Clarification of Isolated tumor cells (ITC). - Subdivision of Stage I into IA and IB (IB includes T0-T1 with N1mi nodal micrometastases). Otherwise, no changes in TNM or Overall Stage - New cM0(i+) category for circulating tumor cells or incidentally discovered metastatic cells in other tissue - Clarification of assigning staging after neoadjuvant therapy (yc or ypTNM) |
|
Luminal A type
|
ER+ and/or PR+, HER2–. Usually low grade. These express genes similar to normal cells lining breast ducts and glands
|
|
Luminal B type
|
ER+ and/or PR+, HER2+. These are similar to luminal A, but grow faster and have a slightly poorer prognosis.
|
|
Basal type
|
ER–, PR–, HER2–, cytokeratin 5/6 positive, and/or HER1+. Also known as "triple negative". Higher prevalence in young African American women.
|
|
HER2 type
|
ER-, PR-, HER2+. Usually high histological grade.
|