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87 Cards in this Set

  • Front
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acute nephritic syndrome
type of renal failure with glomerular inflammation
acute renal failure
sudden rapid deterioration of kidney function that is sometimes reversible
acute tubular necrosis
type of acute renal failure in which there is actual damage to the kidney tubules
anuria
total urine output less than 50ml in 24 hours
arteriovenous fistula
type of vascular access for dialysis; created by surgically connecting an artery to a vein.
arteriovenous graft
type of surgically created vascular access for dialysis by which a piece of biologic, semibiologic, or synthetic graft material connects the patient's artery to a vein
azotemia
abnormal concentration of nitrogenous wastes in the blood
chronic kidney disease
chronic progressive and irreversible diseases of the kidneys
Continuous ambulatory peritoneal dialysis
method of peritoneal dialysis whereby a patient manually performs four or five complete exchanges or cycles throughout the day
continuous cyclic peritoneal dialysis
method of peritoneal dialysis in which a peritoneal dialysis machine (cycler) automatically performs exchanges, usually while the patient sleeps
continuous renal replacement therapy
variety of methods used to replace normal kidney function by circulating the patient's blood through a filter and returning it to the patient
dialysate
solution that circulates through the dialyzer in hemodialysis and through the peritoneal membrane in peritoneal dialysis
dialyzer
"artificial kidney" or dialysis machine; contains a semipermeable membrane through which particles of a certain size can pass
diffusion
movement of solutes (waste products) from an area of higher concentration to an area of lower concentration
effluent
term used to describe the drained the drained fluid from a peritoneal dialysis exchange
end-stage renal disease
final stage of renal failure that results in retention of uremic waste products and the need for renal replacement therapies
exchange (peritoneal dialysis)
complete cycle of peritoneal dialysis includes fill, dwell, and drain phases
glomerulonephritis
inflammation of the glomerular capillaries
hemodialysis
procedure during which a patient's blood is circulated through a dialyzer to remove waste products and excess fluid
interstitial nephritis
inflammation within the renal tissue
nephrosclerosis
hardening of the renal arteries
nephrotic syndrome
type of renal failure with increased glomerular permeability and massive proteinuria
nephrotoxic
any substance, medication, or action that destroys kidney tissue
Osmosis
movement of water through a semipermeable membrane from an area of lower solute concentration to an area of higher solute concentration
peritoneal dialysis
procedure that uses the lining of the patient's peritoneal cavity as the semipermeable membrane for exchange of fluid and solutes
peritonitis
inflammation of the peritoneal membrane (lining of the peritoneal cavity)
pyelonephritis
inflammation of the renal pelvis
ultrafiltration
process whereby water is removed from the blood by means of a pressure gradient between the patient's blood and the dialysate
uremia
an excess of urea and other nitrogenous wastes in the blood
urinary casts
proteins secreted by damaged kidney tubules
The renal system helps ?
regulate the body's internal environment and is essential for the maintenance of life
what is fluid overload ?
the patient whose fluid intake exceeds the ability of the kidneys to excrete fluid
fluid volume deficit
fluid intake is inadequate, the patient is said to be volume depleted and may show signs and symptoms
Why is the fluid intake and output (I&O) record important ?
A key monitoring tool, is used to document important fluid parameters, including the amount of fluid taken in (orally or parenterally), the volume of urine excreted, and other fluid losses (diarrhea, vomiting, diaphoresis)
Is a patients weight important with renal disorders ?
Yes - documenting trends in weight is a key assessment strategy essential for determining the daily fluid allowance and indicating signs of fluid overload or deficit
With aging the kidney is less able to what ?
Respond to acute fluid and electrolyte changes
Elderly patients may develop what ?
Atypical and nonspecific signs and symptoms of disturbed renal function and fluid and electrolyte imbalances
A fluid balance deficit in the elderly can lead to ?
constipation, falls, medication toxicity, urinary tract and respiratory tract infections, delirium, seizures, electrolyte imbalances, hyperthermia, and delayed wound healing
Chronic kidney disease (CKD) is ?
an umbrella term that describes kidney damage or a decrease in the glomerular filtration rate (GFR) for 3 or more months
CKD is associated with what ?
decreased quality of life, increased health care expenditures, and premature death
Untreated CKD can result in ?
end-stage renal disease (ESRD) and necessitate renal replacement therapy (dialysis or kidney transplantation)
Risk factors of untreated CKD
cardiovascular disease, diabetes, hypertension, and obesity
what percentage of the U.S. population aged 20 years and older have CKD ?
16.8 %
Sodium deficit manifestations
Nausea, malaise, lethargy, headache, abdominal cramps, apprehension, seizures
Sodium deficit management
diet, normal saline or hypertonic saline solutions
sodium excess manifestations
dry, sticky mucous membranes, thirst, rough dry tongue, fever, restlessness, weakness, disorientation
sodium excess management
fluid, diuretics, dietary restriction
Potassium deficit manifestation
anorexia, abdominal distention, paralytic ileus, muscle weakness, ECG changes, dysrhythmias
Potassium deficit management
diet, oral or parenteral potassium replacement therapy
Potassium excess manifestation
diarrhea, colic, nausea, irritability, muscle weakness, ECG changes
Calcium deficit manifestations
Abdominal and muscle cramps, stridor, carpopedal spasm, hyperactive reflexes, tetany, positive Chvostek's or Trousseau's sign, tingling of fingers and around mouth, ECG changes
Calcium deficit management
diet, oral or parenteral calcium salt replacement
Calcium excess manifestation
Deep bone pain, flank pain, muscle weakness, depressed deep tendon reflexes, constipation, nausea and vomiting, confusion, impaired memory, polyuria, polydipsia, ECG changes
Calcium excess management
fluid replacement, etidronate, pamidronate, mithramycin, calcitonin, glucocorticoids, phosphate salts
Bicarbonate deficit manifestation
Headache, confusion, drowsiness, increased respiratory rate and depth, nausea and vomiting, warm flushed skin
Bicarbonate deficit management
Bicarbonate replacement, dialysis
Bicarbonate excess manifestation
Depressed respirations, muscle hypertonicity, dizziness, tingling of fingers and toes
Bicarbonate excess management
fluid replacement if volume depleted; ensure adequate chloride
Protein deficit manifestations
Chronic weight loss, emotional depression, pallor, fatigue, soft flabby muscles
Protein deficit management
diet, dietary supplements, hyperalimentation, albumin
Magnesium deficit manifestations
dysphagia, muscle cramps, hyperactive reflexes, tetany, positive Chvostek's or Trousseau's sign, tingling of fingers, dysrhythmias, vertigo
Magnesium deficit management
diet, oral or parenteral magnesium replacement therapy
Magnesium excess manifestations
Facial flushing, nausea and vomiting, sensation of warmth, drowsiness, depressed deep tendon reflexes, muscle weakness, respiratory depression, cardiac arrest
Magnesium excess management
Calcium gluconate, mechanical ventilation, dialysis
Phosphorus deficit manifestations
Deep bone pain, flank pain, muscle weakness and pain, paresthesia, apprehension, confusion, seizures
Phosphorus deficit management
diet, oral or parenteral phosphorus supplementation therapy
Phosphorus excess manifestations
Tetany, tingling of fingers and around mouth, muscle spasms, soft tissue calcification
Phosphorus excess management
diet restriction, phosphate binders, normal saline solution, IV dextrose solution, and insulin
What is the primary cause of CKD ?
Diabetes
Percentages of type 1 diabetes patients that will develop kidney damage ?
Between 25% and 40%
Percentages of type 2 diabetes patients that will develop kidney damage ?
5% to 40%
What is the leading cause of renal failure in patients starting renal replacement therapy ?
Diabetes
The second leading cause of renal failure in patients starting renal replacement therapy ?
hypertension, followed by glomerulonephritis and pyelonephritis; polycystic, hereditary, or congenital disorders; and renal cancers
Pathophysiology of CKD
It is not yet clearly understood, but the damage to the kidneys is thought to be caused by prolonged acute inflammation that is not organ specific and thus has subtle systemic manifestations
How many stages of chronic kidney disease our there ?
5 stages
When does stage 5 result ?
Results when the kidneys cannot remove the body's metabolic wastes or perform their regulatory functions and renal replacement therapies are required to sustain life.
Stage 1 CKD
GFR greater than or equal too 90 ml

Kidney damage with normal or increased GFR
Stage 2 CKD
GFR equal too 60-89 ml

Mild decrease in GFR
Stage 3 CKD
GFR equal too 30-59 ml

Moderate decrease in GFR
Stage 4 CKD
GFR equal too 15-29 ml

Severe decrease in GFR
Stage 5 CKD
GFR less than 15 ml

Kidney failure (end-stage renal disease [ESRD] )
Patients with CKD are at increased risk for ?
cardiovascular disease, the leading cause of morbidity and mortality
What can help to slow CKD disease progression and improve patient outcomes ?
treatment of hypertension, anemia, and hperglycemia and detection of proteinuria
What does an elevated serum creatinine level indicate ?
underlying kidney disease ; as the creatinine level increases, symptoms of chronic kidney disease begin
Symptoms of CKD that begin as creatinine levels increase are ?
Anemia - due to decreased erythropoietin production by the kidney

Metabolic acidosis , and abnormalities in calcium and phosphorus herald the development of CKD
Fluid retention, evidenced by both edema and congestive heart failure develops
As CKD progresses you will see ?
Abnormalities in electrolytes occur, heart failure worsens and hypertension becomes more difficult to control
Assessment and diagnostic findings of CKD
GFR is the amount of plasma filtered through the glomeruli per unit of time. Creatinine clearance is a measure of the amount of creatinine the kidneys are able to clear in a 24 hour period.
Normal values differ in men and women.