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4 Cards in this Set
- Front
- Back
Most common infections (uti's)
[Upper?] [Lower] |
[Upper:]
Acute pyelonephritis Acute bacterial prostatitis [-Lower:] Acute cystitis Acute urethral syndrome -Recurrent urinary tract infections (UTIs) Trimethoprim/sulfamethoxazole is frequently the treatment of choice for oral therapy of UTIs. Fluoroquinolones often used as well |
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Urinary Tract Antiseptics:
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Nitrofurantoin [Furadantin]
Methenamine [Mandelamine] Nalidixic acid [NegGram] Cinoxacin [Cinobac] |
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Methenamine [Mandelamine]
[Overview] [Uses] [AV] |
*Has multiple actions*
Decomposes into ammonia and formaldehyde, which denature bacteria Uses: chronic lower UTIs Adverse effects: SAFE Well tolerated Contraindicated in? Renal patient – Liver dysfunction |
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Nitrofurantoin
[Action] |
*Has multiple actions*
-Nitrofurantoin is activated by bacterial enzymes, = inactivates proteins. -Inactivations cause the inhibition of biochemical processes of aerobic energy metabolism and the syntheses of bacterial DNA,RNA, cell wall, and protein. -Nitrofurantoin interferes with a variety of bacterial processes, this may explain the lack of acquired bacterial resistance. -Typically used only in UTI, and UTI prophylaxis |