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59 Cards in this Set

  • Front
  • Back

Endocrine Glands

Ductless glands that secrete hormones directly into the blood stream

Hormones

Chemical messenger sent to many parts of the body to produce a specific effect on a target cell or organ

Endocrine system

In vertebrates, a system that works in parallel from the nervous system to maintain homeostasis by releasing chemical hormones from various glands

Negative feedback mechanisms

Mechanism of homeostasis response by which the output of a system suppresses or inhibits the activity of the system

Antidiuretic hormone (ADH)

Hormone regulated by the hypothalamus and released by the pituitary gland that increases the permeability of the distal tubule and the collecting duct in the nephrons of the kidney, allowing more water to be reabsorbed into the bloodstream from the filtrate

Tropic hormones

Hormone that targets endocrine glands and stimulates them to release other hormones

Pituitary gland

Consists of both the anterior and posterior pituitary, both of which produce hormones that influence metabolism, growth, development, reproduction and other life functions.

Posterior pituitary

Posterior lobe of the pituitary, an endocrine gland that stores and releases ADH and oxytocin, which are produced by the hypothalamus and transferred to the posterior pituitary by neural axons

Anterior pituitary

An endocrine gland that synthesizes and secretes 6 major hormones: human growth hormone (hGH), prolactin (PRL), thyroid stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), follicle stimulating hormone (FSH), and luteinizing hormone (LH)

Human growth hormone

Stimulates the liver to secrete hormones called growth factors, which along the hGH influence many physiological processes such as protein synthesis, cell division and growth, and metabolic breakdown and release of fats

Thyroid gland

Butterfly shaped gland located below the larynx in the neck, produces thyroxine and helps regulate metabolism and growth

Thyroxine

Hormone produced by the thyroid and released into the bloodstream: controls the rate that the body metabolizes fats, carbohydrates and proteins for energy

Hypothyroidism

Condition when the thyroid produces to low of a level of thyroxine

Hyperthyroidism

When the thyroid produces extremely high levels of thyroxine

Thyroid stimulating hormone (TSH)

Released by the anterior pituitary which causes the thyroid gland to secrete thyroxine; controlled by the negative feedback mechanism, the rising levels of thyroxine are detected in the blood by the hypothalamus and anterior pituitary suppress the secretion of TSH and thyroxine

Goitre

Enlargement of a thyroid gland caused when the thyroid gland is constantly stimulated by TSH, but is unable to synthesize thyroxine to create a negative feedback loop

Adrenal glands

One pair of organs located on top of the kidneys; composed of two layers (an outer cortex and an inner medulla); each layer produces different hormones and functions as an independent organ

Adrenal medulla

Inner layer of the adrenal glands that produces epinephrine and norepinephrine hormones that regulate the short term stress response

Epinephrine

Hormone produced by the adrenal cortex hormones that regulates the short term stress response

Norepinephrine

Aka noradrenaline: regulates the short term stress response

Short term stress response

The bodies acute reaction to stress in which the sympathetic nervous system is stimulated (fight or flight response)

Adrenal cortex

The outer layer of the adrenal glands that produce glucocorticoids and mineralocorticoids, hormones that regulates long term stress response: also secretes small amounts of gonadocorticoids: female and male sex hormones that supplement the hormones produced by the testis and ovaries

Long term stress response

Sustained physiological response to stressors, characterized by increases to blood glucose and blood pressure and decrease in inflammatory response; regulated by hormones produced by the adrenal cortex

Cortisol

A type of glucocorticoid hormone released by the adrenal cortex of the adrenal gland in a long term stress response; triggers an increase in blood glucose levels and reduces inflammation

Adrenocorticotropic hormone (ACTH)

Hormone synthesized by the anterior pituitary gland to target the adrenal cortex and regulate the production of glucocorticoids

Aldosterone

A type of mineralocorticoid hormone secreted by the adrenal cortex; stimulates the distal tubule and collecting duct of the kidneys to increase the absorption of sodium into the bloodstream which is followed by the passive absorption of water and chloride

Pancreas

A small gland in the abdomen that secretes digestive enzymes into the small intestine; as well as bicarbonate to neutralize hydrochloric acid from the atom; also secretes the hormone insulin

Islets of langerhans

Cluster of endocrine cells found throughout the pancreas; consisting of glucagon- producing alpha cells and insulin-producing beta cells

Beta cells

Cell of the pancreas which secretes insulin to decrease the level of blood glucose

Alpha cell

Cell of the pancreas which secretes glucagon to increase the level of blood glucose

Insulin

A hormone secreted by the alpha cells of the islets of langerhans in the pancreas to make target cells more permeable to glucose; enables the body to use sugar and other carbohydrates

Glucagon

Hormone produced by the alpha cells of the islets of langerhans in the pancreas to stimulate the liver to convert glycogen back into glucose which is released into the blood

Diabetes mellitus

A condition that results when the pancreas doesn’t make enough insulin or the body doesn’t respond properly to insulin. Levels of glucose tend to rise sharply after meals (hyperglycaemia) and remain at significantly elevated levels

Hyperglycaemia

Condition from high levels of blood glucose, occurs in individuals with diabetes mellitus

Type 1 diabetes

A condition where the immune system produces antibodies that attack and destroy the beta cells of the pancreas so they’re unable to produce insulin. This requires daily insulin injections

Type 2 diabetes

A condition that develops slowly over time either because the insulin receptors stop responding to insulin or Because the beta cells produce less and less insulin over time

GOAT FLAP

G- growth hormone “hGH”


O- Oxytocin


A- anti diuretic hormone “ADH”


T- Thyroid stimulating hormone “TSH”



F- Follicle Stimulating Hormone “FSH”


L- Luteinizing Hormone “LH”


A-Adrenocorticotropic hormone “ACTH”


P- Prolactin “PRL”

What does the human growth hormone do “hGH”

Stimulates cell division, bone and muscle growth and metabolic functions

What does parathyroid hormone do “PTH”

Raises blood calcium levels by stimulating the bone cells to release calcium, the intestines absorb calcium from food, and the kidneys to reabsorb calcium

What does the adrenal cortex secrete

Glucocorticoid, mineralocorticoids and gonadocorticoids

What does glucocorticoids do

Stimulate tissues to raise blood glucose and break down protein


Ex. Cortisol

What do mineralocorticoids do

Promotes reabsorption of sodium in the kidneys (raises blood pressure)

What does adrenocorticotropic do “ACTH”

Stimulates the adrenal cortex to secrete glucocorticoids

What does follicle stimulating hormone do “FSH”

Stimulates the production of ova and sperm

What does luteinizing hormone do “LH”

Stimulates sex hormone production

What does prolactin do “PRL”

Stimulates milk production from the mammary gland

What does antidiuretic hormone do “ADH”

Promotes the retention of water from the kidneys

What does oxytocin do

Stimulates uterine muscle contractions and the release of milk from the mammary glands

What does the thyroid secrete

Thyroxine and Calcitonin

Thyroxine (t4) what does it do

Affects all tissues, increases metabolic rate and increases growth and development

What does calcitonin do?

Targets bones and kidneys to lower blood calcium by inhibiting release of calcium from bone and reabsorption on calcium by kidneys

What do gonadocorticoids do

Promote sexual characteristics

What does the adrenal medulla secrete

Epinephrine and norepinephrine

What does epinephrine and norepinephrine do

They are our fight or flight hormones and they raise blood glucose levels

What does the pancreas secrete

Insulin and glucagon

What does insulin do

Lowers blood glucose levels and promotes glycogen to form in the liver

What does glucagon do

Raises blood glucose levels by converting glycogen into glucose

What do the ovaries secrete

Estrogen and progesterone

What’s the order of the negative feed back loop

Hypothalamus


(Releasing hormone “hormone 1)”


Pituitary gland


(Stimulating hormone “hormone 2”)


Target gland


(Hormone 3)<— feeds back to hypothalamus and pituitary gland