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38 Cards in this Set
- Front
- Back
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What does the sensitivity requirement test measure?
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Determines the load that will cause a change of one division from the rest position
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What does the Rider and Graudated Beam test measure?
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Determines the agreement between the dial and the weights placed on the balance
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What is compounding?
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Mixing/preparing a drug as a result of a prescription order from a practitioner or in anticipation of a prescription order.
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What is manufacturing?
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Preparation of a drug/drug device from substances of natural origin or through chemical or biological synthesis.
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What do dosage form do for drug administration?
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1. Protect from environment
2. Protect from GI degradation 3. Conceal taste/odor 4. Provide liquid preparations 5. Provide clear liquid preps 6. Provide rate-controlled action 7. Optimal topical drug action 8. Allow insertion into orifices 9. Provide direct entry to blood 10. Optimal inhalation therapy |
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What is an active ingredient?
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Component used for cure/treatment or as nutritional supplement
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What is an added substance?
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Inactive ingredient necessary for preparation (enhance stability); should not elicit a therapeutic response
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What ingredients may be used in compounding?
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Ingredients certified by USP, NF, FCC, ACS, and/or AR; drugs that are chemically pure, technical, food, or cosmetic grade
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Freezer storage
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-25C to -10C
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Cold storage
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Not exceeding 8C
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Refrigerator storage
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2C to 8C
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Cool storage
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8C to 15C (may be refrigerated unless noted otherwise)
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Room temperature
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The ambient temperature in the room
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Controlled Room Temperature
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20C to 25C
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Warm storage
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30C to 40C
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Excessive Heat
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>40C
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Dry storage
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Controlled room temp with avg. percent humidity no greater than 40%
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Light resistant container
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Protect from light
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Well closed container
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Protect from solids getting in or out
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Tight container
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Protect from solid, liquids, or vapors from getting in or out
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Hermetic container
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Impervious to gas or air (most secure type of container)
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What is mandated for lab and pharmacies according to the Hazard Communication Standard?
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1. Inventory of hazardous materials
2. MSDS for hazardous materials 3. Warning labels on products 4. Written program of HCS compliance 5. Employees informed about hazardous materials 6. Employees informed about elements of HCS |
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What are the steps in compounding?
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1. Preparatory
2. Compounding 3. Final Check 4. Sign Off 5. Clean Up |
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Who was the Greek physician who is credited with the introduction of scientific pharmacy and medicine and introduced ethics?
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Hippocrates
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What are ointments, creams, gels, and pastes?
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Semisolid dosage forms intended for topical application (skin, surface of the eye, nasally, vaginally, rectally)
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What is a topical drug?
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Delivers drug into the skin
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What is a transdermal drug?
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Delivers drug through the skin
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Hydrocarbon bases...
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Oleaginous, have an emollient effect, protect from escape of moisture, occlusive, don't dry out, difficult to wash with water
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What is a levigating agent?
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Helps with the incorporation of powdered substance into the base
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Absorption bases...
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Used an emollients, do not provide a lot of occlusion, difficult to wash with water, useful to incorporate small volumes of aqueous solution into hydrocarbon bases
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What are the different particle sizes?
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Very coarse, coarse, moderately coarse, fine, and very fine
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What is trituration?
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Grinding a drug in a mortar to reduce its particle size.
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What is levigation?
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Used in ointments to reduce the particle size and grittiness of added powders
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What is spatulation?
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Small amounts of powders may be blended by the movement of a spatula through the powders on a sheet of paper or an ointment tile
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What is sifting?
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Passing powder through a sifter creating a light, fluffy product.
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What is tumbling?
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The powder is enclosed in a rotating containing.
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What are three types of medicated powders?
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Internal, External, Inhalation
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What is a granule?
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Smaller, irregularly shaped particles of powder; flow better than powders; more easily "wetted" by liquids
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