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39 Cards in this Set
- Front
- Back
Example of naturally required immunity?
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Maternally derived antibody in a newborn infant
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Resistance to infection following recovery from viral infection is known as
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Naturally acquired active immunity
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The major cellular component of adaptive immunity is
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Lymphoctye
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The major humoral component of adaptive immunity is
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Antibody
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In which organ do T lymphocytes mature?
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Thymus
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A hapten is
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An antigenic determinant capable of stimulating an immune response only when bound to a carrier molecule
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Immunogenic refers to
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The ability of a substance to cause an immune response
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The hypervariable regions of an immunoglobulin are:
1. All important parts of the Ag bind site of an Ab 2. Found in both heavy chains 3. The same in IgG and IgM produced by plasma cell after it switches from IgM synthesis to IgG synthesis 4. All of the above |
All of the above
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Which immunoglobulin class(es) has/have a J chain?
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IgA & IgM
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Which immunoglobulin help initiate the complement pathway?
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IgG & IgM
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The 5 immunoglobulin classes in order of decreasing concentration
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IgG > IgA > IgM > IgD > IgE
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How many potential antigen binding sites does an IgG molecule have?
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Two
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The normal ratio of helper:cytotoxic cells
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2:1
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T cells are incapable of
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Secretions of immunoglobulins
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The immunoglobulin class that associates with allergic reactions is
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IgE
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T helper cells have which kind of surface markers ?
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CD4
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Humoral antibody are produced by which cell line ?
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B lymphocytes
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Which immunoglobulin is a pentamer ?
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IgM
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The proper term for the cell surface markers referred to as "self antigen" is
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Major histocompatibility complex
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Which is most actively phagocytic leukocyte and antigen processing cell originating in the blood?
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Monocyte
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Which immunoglobulin is considered part of the nonspecific immune system ?
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IgA
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The most defense functions of monocytes/macrophages include:
1. antigen presentation 2. phagocytosis 3. induction of the immune response 4. secretion of biologically active substances 5. all of the above |
All of the above
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Which complement component is present in the greatest concentration in normal patient serum ?
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C3
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Which complement component is not part of the Lectin pathway ?
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C1
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Thymus is primary or secondary lymphoid tissue ?
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Thymus
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Which lymphocytes are considered part of nonspecific immune response because they destroy ay infected cell regardless of the antigen causing the infection ?
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Natural killer cells
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Which tissue cell does not originate in the blood and is capable of phagocytosis and presentation of an antigen ?
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Neutrophil
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Which complement component is not part of the MAC:
a. C5 b. C9 c. C6 d. C4 |
C4
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Which complement component is exclusive to the alternative pathway ?
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Factor B
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Actively involved in parasitic infection
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Eosinophil
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Actively involved in bacterial infections
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Neutrophils
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Referred to as MAST cell when present in tissue
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Basophil
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Referred to as a macrophages when present in tissue
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Monocyte
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Main cellular component of cell mediated immunity
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T lymphocytes
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Main component of humoral immunity
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B lymphocytes
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Mediates inflammation by causing MAST cells to release histamine
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Anaphylatoxin
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Enhance phagocytosis by coating the surface of foreign particles
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Opsonin
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Disrupt cell membrane resulting in destruction of cell
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Cytolysis
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Stimulate the migration of phagocytic cells to the damaged area
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Chemotaxins
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