Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
6 Cards in this Set
- Front
- Back
What are the Non-extracorporeal methods of enhanced toxin elimination?
|
1. Multi-dose activated charcoal {MDAC} : "gastrointestinal dialysis"
2. peritoneal dialysis |
|
List the extracorporeal methods of enhanced toxin elimination.
|
1. Haemodialysis [HD]
2. Haemoperfusion [HP] 3. Exchange Transfusion 4. Continuous veno-venous Haemofiltration [CVVH} 5. CAVH |
|
Mnemonic for Toxins eliminated by Haemodialysis and Haemoperfusion?
|
" COP, I'VE STUMBLED"
|
|
COP I'VE STUMBLED ?
|
Carbamazepine
Osmol Gap [increased] Propylene glycol Isopropanol Valproate *** Excess Acid = [severe metabolic acidosis] Salicylates *** Theophylline Uraemia [nephrotoxic drugs] Methanol *** Barbituates Lithium *** Ethylene Glycol *** Diethylene / triethylene glycols |
|
2 Mechanisms for MDAC?
|
1. Interrupts enterohepatic circulation for liver metabolised drugs
2. assists gastrointestinal mucosa to work as a "dialyser" : hence "gastrointestinal dialysis" |
|
Which drugs in overdose can MDAC be used?
|
1. Carbamazepine
2. Phenytoin 3. Phenobarbitone 4. Theophylline 5. Dapsone 6. Piroxicam 7. Yellow Oleander |