Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
24 Cards in this Set
- Front
- Back
What is the best way to differentiate between Campylobacter and Helicobacter
|
Presence of Flagellar Sheets
Camp - Absent Heli - Present |
|
What is required for Campylobacter growth
|
5 -10% O2
5 - 10% CO2 80 - 90% N2 |
|
What shaped and Gram Stain are Campylobacter
|
Curved Spiral, motile/unsheathed flagella, gram -
|
|
What is the metabolism of Campylobacter
|
Nonfermentative/nonoxidative
Derive energy from the use of amino acids and 4-6-carbon intermediates of the TCA |
|
What diseases are campylobacter associated with
|
gastroenteritis, abortions in cows, sheep, humans, sepsis, meningitis, periodontal disease and proctitis (homosexual)
|
|
What is the habitat of Campylobacter
|
Campylobacters are normal flora in GI tracts
|
|
What is a good test to differentiate between Camplyobacter coli and Campylobacter jejuni
|
Test Hippurate
C. coli Hippurate - C. jejuni Hippurate + |
|
How many types of transmission are there for Campylobacter
|
2 exogenous and endogenous
|
|
Exogenous Transmission
|
acquire from handling infected animals or through the fecal-oral route
|
|
Endogenous Transmission
|
Transmission from mother to fetus through genitourinary tract
|
|
What are pathogenic factors of Campylobacter
|
LPS - protects from stomach acid
Flagellar Motion/Shape - passes through mucous membrane Distending Cytotoxin -stops cell divisioin Enterotoxin - similar to cholera, ETEC, and LT Adhesins - attachment |
|
Symptoms of Campylobacter infection
|
watery diarrhea, bloody diarrhea, extraintestinal disease
80% of patients are asymptomatic |
|
Diseases caused by campylobacter
|
Acute Enteritis, Appendicitis like syndrome, Bacteremia, septic abortion, Reactive arthiritis
|
|
Lab Idnetification of campylobacter
|
From stool: Campy-Thio, Campy-BAP in 5% O2, 10% CO2, 85% N2
|
|
What is Campy-BAP?
|
10% Sheep's Blood, Vancomycin (inhibits Gram +), trimethoprim (e. coli), polymyxin B, cephalothin, amphotericin B (fungi), in Brucella Agar base
|
|
What is the most important pathogen of campylobacter/ what does it causes
|
C. jejuni
Isolated from stoll 7 times more than Salmonella shigella Guillain-Barre syndrome |
|
Treatment for Campylobacter
|
usually just fluid and electrolyte replacement.
If antibiotics: erythromycin and quinolones |
|
_______ causes peptic ulcers
|
Helicobacter
|
|
Growth environment contains _____, _____, and ______ at _____ temperature
|
10% CO2, 5% O2, 85% N2
35-37 C, 42 C High Humidity |
|
_____cytotoxin in H. pylori causes _____
|
Vacuolating, cellular damage
|
|
_____ causes activates signal transudction.
This can cause ____ |
Cag A
cellular growth, maybe cancer |
|
H. pylori can be cultured on :_______ + 5% Sheep Blood
________+ 7% Horse Blood ________ + antibitic |
Mueller Hinton
Brain Heart Infusion Thayer-Martin |
|
___ and helps protect H. pylori by hydrolizing Urea to __ and __.
|
Urease
ammonia CO2 |
|
_____, _____, and _____ are treatments for H. pylori
|
Bismuth, Amoxicillin, and Tetracyclin
|