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34 Cards in this Set
- Front
- Back
hemoglobin is also known as |
respiratory pigment |
|
identified respiratory pigment |
Felix seyler |
|
Reference method of hemoglobin determination |
cyanmethemoglobin |
|
reagent of cyanmethemoglobin |
drabkin's (potassium ferricyanide) |
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converts hemoglobin to methemoglobin |
Potassium ferricyanide (K3Fe) |
|
all hemoglobin is measured except |
sulfhemoglobin |
|
high wbc count correcction |
centrifuge and measure supernatant |
|
lipemia correction |
0.01 patient plasma + 5 ml cyanmethemoglobin reagent |
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abnormal globulin correction |
0.1 g potassium carbonate to drabkins reagent |
|
method that does not produce toxic waste. Used in some automated instruments |
sodium lauryl sulfate (SLS) |
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Slowest hemoglobin |
hgb A2 hgb C hgb E hgb O hgb C(harlem) |
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differentiates hemoglobin S,D,G, C, E |
citrate agar |
|
migrate to the same area at cellulose acetate electrophoresis |
Hgb S Hgb D Hgb G |
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HEME a.k.a |
ferroprotoporphyrin IX |
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site of heme synthesis |
Mitochondria |
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Globin syntheis production of A and Z globin |
Chromosome 16 |
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Globin synthesis Production of B,E,D and G |
Chromosome 11 |
|
2 zeta 2 gamma |
Portland |
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2 alpha 2 epsilon |
Gower 2 |
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Hgb bound to oxygen Found in arterial blood "Relaxed state" |
Oxyhemoglobin |
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Hgb not bound to oxygen In venous blood "Tense state" |
Deoxygenated hemoglobin |
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Hgb bound to CO 240 times greater affinity Tasteless, colorless, odourless |
Carboxyhemoglobin |
|
Mixture of oxidized, partially denatures forms of hemoglobin |
Sulfhemoglobin |
|
Prolonged constipation Enterogenous cyanosis Color of blood: mauve lavender |
Sulfhemoglobin |
|
Color of blood: cherry red |
Carboxyhemoglobin |
|
Cells containing HB S and C |
make 1:2 dilution with distilled water and multiply by 2 |
|
Fastest hgb |
Hemoglobin A1 |
|
aka heme syntetase |
ferrochelatase |
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enzyme needed to insert Fe (ferrous) to the protophorphyin IX |
ferrochelatase |
|
2 zeta 2 epsilon |
Gower 1 |
|
2 alpha 2 gamma |
High F |
|
2 alpha 2 beta |
A1 |
|
2 alpha 2 delta |
A2 |
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Hb with Fe3+, not bound to O2 Color of blood: chocolate brown |
Methemoglobin |