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9 Cards in this Set

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What is inoculation?

Purposely infecting a person with a mild disease (Variola minor) to protext them against a severe disease (Variola major)

What did Edward Jenner discover?

-Noticed milkmaids seldom get smallpox, this is because they are already infected with cowpox.


-Inoculated someone with cowpox and this person was then injected with smallpox and remained asymptomatic- birth of vaccination!

What are the 3 strategies that the immune system uses to protect the body from infection?

1. protective barriers


2. innate immune response


3. adaptive immune response

What does sebum do? (secreted by sebaceous glands in the skin)

1) fatty acid (oily protective barrier


2) antibacterial, antifungal


3) lower skin pH


4) most microorganisms grow best at neutral pH

What do goblet cells do?

secrete mucous and trap microbes

What are ciliary escalators?

ciliated epithelial cells in trachea and nasopharynx


-cilia push bacterial cells back up, they get trapped in mucous and coughed out of swallowed (then killed by stomach acid)

How does normal flora help to prevent infection?

-microbial antagonism: normal flora inhibits colonization by pathogenetic microorganisms through:


-normal flora educates our adaptive immune responseW

Define the immune system

the cells, tissues and molecules that mediate resistance to infection

What do microbial flora do?

inhibit pathogen invasion by occupying GI space and thereby preventing pathogens from colonizing the host