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15 Cards in this Set
- Front
- Back
CD2 (LFA-2)
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secreted by: T cells, thymocytes, NK cells
function - adhesion molecule |
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CD3
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secreted by: Teccls, thymocytes
function - signal transduction by TCR |
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CD4
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secreted by: TH cells, thymocytes, monocytes, macrophages
function - coreceptor for TCR-MHC II, receptor for HIV |
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CD8
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secreted by: CTLs, thymocytes
function - coreceptor for MHC I |
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CD14 (LPS receptor)
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secreted by: moocytes, macrophages, granulocytes
function - binds LPS |
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CD16
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secreted by nK cells, macrophages, neutrophils
function - opsoniation, ADCC |
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CD 18
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secreted by leukocytes
function - cell adhesion |
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CD 19
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expressed on B cells
function - coreceptor w./ CD21 for B cell activation |
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CD 20
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expressed on B cells
function - role in B cell activation |
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CD21
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found on mature B cells
function -receptor for complement C3d, complexes w/ CD19, EBV receptor |
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CD28
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found on T cells
function - receptor for costimulatory B7 |
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CD34
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found on precursors of hematopoeitic cells, endothelial cells in HEV
function - cell cell adhesion, binds L-selectin |
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CD40
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found on B cells, macrophages, dendritic cells, endothelial cells
function - binds CD40L, role in T cell dependent B cell, macrophage, dendritic cell and endothelial cell activation |
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CD45
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found on hematopoietic cells
function - critical role in T and B cell antigen receptor mediated signaling |
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CD56
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found on NK cells
function - not known |