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240 Cards in this Set

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What is murine mycoplasmosis in rats caused by?

Mycoplasma

What two major areas are affected by murine Mycoplasma?

Respitory and genital

What animal does murine Mycoplasma affect?

Pet and housed rats

What kind of tumors are common in most strains of rats?

Mammary tumors

Mammary tumors rarely______.

Metastisize

Who is the animal welfare act enforced by?

A division of the USDA called the animal and plant Health inspection Service (USDA-APHIS)

What organization promotes the humane treatment of animals in science?

American Association for Accreditation of Laboratory Animal Care (AAALAC)

The American Association for Accreditation of Laboratory Animal Care is a __________ assessment facilities and companies go through to become accredited.

Voluntary

What organization reviews animal research protocols?

Institutional Animal Care and Use Committee (IACUC)

What organization certifies laboratory technicians and includes researchers and technicians in its membership?

American Association for Laboratory Animal Science (AALAS)

What is the most common health condition that affects people working in a research animal facility?

Laboratory Animal Allergy (LAA)

What percentage of people working in a research animal facility develope allergy symptoms?

10-30%

What are outbred strains?

The result of random mating to achieve genetic variations.

What are inbred strains of mice?

The result of brother/sister, father/daughter, and mother/son matings for a minimum of 20 consecutive generations.

Animals that genetically differ at one particular location of gene on a chromosome are called ________ ________.

Congenic strains

The result of microinjections of DNA into mouse eggs for the production of very specific disease models are called _________ _________.

Transgenic strains

Transgenic strains are useful in studying some forms of ________.

cancer

What are axenic animals?

Germ free animals

Axenic animals are derived from ____________ so that they are free from infection by any microorganisms.

Hysterectomy

Germ free mice that have been introduced to one or more known nonpathogenic microorganisms are called ___________ mice.

Gnotobiotic

Animals free from specific pathogenic organisms are called

Specific pathogen free (SPF) and viral antibody free (VAF)

Animals maintained under sterile conditions in a barrier unit are called ______ _____ animals.

Barrier sustained

Animals Houser with no special precautions are called __________ animals.

Conventional.

Dominant mouse will occasionally remove the _________ _______ from all other mice in cage.

Facial hair

What is it called when the facial hair is removed by a dominant mouse?

Barbering

Mice should be picked up by the _____ of tail and never the middle or tip of tail.

Base

A mouse can be placed over a ______ _____ so that its front feet can grip something.

Wire grid

What is it called when female mice are exposed to a male mouse so they will come into estrus within 72 hours?

Whitten effect

What is it called If a recently bred female is exposed to another male and the pregnancy doesn't take and she returns to estrus in 4-5 days?

Bruce effect

The gestation of a mouse is

19-21 days

Mice will have litter sizes up to

6-12 pups

Postpartum estrus in mice occurs within _____ hours of parturition.

24

Mice are weaned at ______ days.

21

The oral and gastric gavage goes directly into the _______.

Stomach

During the administration of a oral and gastric gavage, one needs to use a ________ Dosing needle attached to a_________.

Curved, syringe

Subcutaneous injections in mice need to be administered over the _________ area.

Shoulder

Intramuscular injections in mice need to be administered in the inner or posterior ___________.

Thigh.

Intraperitoneal injections in mice need to be administered in the______ ______ ______ of ________.

Lower right quadrant of abdomen

Intravenous injections in mice need to be administered in the ________ _______ vein or ________ vein.

Lateral tail vein, saphenous vein

Signs of pain and distress in mice include a _________ posture, _________, ________, and _____ from group.

Hunched, lethargy, depression, withdrawal

Respitory disease on mice can be _________ or _________.

Viral, bacterial

Clinical signs of respitory disease in mice are _______ and _________.

Dyspnea and chattering

Mouse hepatitis virus can lead to ______ and/or __________.

Encephalitis, hepatitis.

What bacterium causes tyzzer's disease in mice?

Clostridium

what disease in mice causes diahrrea, weight loss, sudden death, and dehydration?

Tyzzers disease

What kind of virus causes epizootic diarrhea of infant mice?

Rotavirus

What are clinical signs of epizootic diarrhea of infant mice?

Soft yellow feces or fecal staining of the anogenital area

How do you treat pinworm in mice?

By deworming and sanitizing

What are the species of mites that can affect mice?

Myobia musculi and myocoptes musculinus

What are clinical signs of mites in mice?

Alopecia, pruritus, and dermatitis.

Where is the lacrimal gland located in rats?

Behind the eyeball

What does the lacrimal gland secrete?

Porphyrin

What does the lacrimal gland do for the rats eye?

Lubricates it

During stress or disease in rats, what happens to the porphyrin?

Overflows and can stain the face

What organ does a rat lack?

Gallbladder

Rats that eat their own feces are called

Coprophagic

What is the length of the estrus cycle for a rat?

4-5 days

The ______ effect is less pronounced in rats.

Whitten

Subcutaneous injections in rats needs to be administered

Over the shoulder area

Intramuscular injections in rats needs to be administered in the

Inner or posterior thigh muscle

Where do Intraperitoneal injections in rats needs to be administered?

Lower left quadrant of abdomen

Where do IV injections in rats need to be administered (4)?

Lateral tail vein, saphenous vein, dorsal penis vein, sublingual vein.

When can simple blood sampling be accomplished in a rat?

When they are awake and restrained

How much blood can be taken out of the saphenous vein in a rat?

1 mL

How much blood can be taken out of the lateral tail vein in a rat?

1 mL

Difficult or painful blood sampling should be done under

Anesthesia

How much blood can be taken out of the retro orbital sinus in a rat?

1mL

How much blood can be taken out of the jugular vein in a rat?

2-3 mL

Blood taken out of the cranial Verna cava vein should not exceed _____% of body weight.

1

How much blood can be taken out of the cardiac in a rat?

3-5 mL

What kind of blood sampling is considered a terminal procedure because of potential damage to the heart?

Cardiac blood sampling

Rats can get what kind of virus?

Parvovirus

What are the coronaviruses that affect rats?

Sialodacryoadentitis virus, rat coronaviruse, the causative agent of rat sialoadenitis virus.

What are clinical signs of a coronaviruse?

Red porphyrin staining of the face and claws.

The ________ virus is usually asymptomatic?

Sendai

Hamsters have a unique

Cheek pouch.

What kind of studies are hamsters useful in?

Hypothermia studies.

When temperatures are under 48 degrees ferenheight when daylight hours shorten, hamsters go into short periods of _______________.

Pseudo-hibernation

Hamsters are _________ artists.

Escape

What kind of glands do hamsters have that they use to mark territory?

Flank and sebaceous glands

Hamsters are extremely deep ___________.

Sleepers

When breeding hamsters, it is best to establish _____________ pairs before sexual maturity to avoid fighting.

Monogamous

The estrus cycle in a hamster is _____ days.

4

Whata is The gestation period of a hamster?

16 days

How big is a hamster's litter size?

4-12 pups

Hamsters wean at _____ days.

21

Where should Subcutaneous injections in hamsters be administered?

Over the shoulder

Where should intramuscular injections in hamsters be administered?

Inner or posterior thigh muscle

Where should intraperitoneal injections in hamsters be administered?

Lower right quadrant of abdomen

Where should intravenous injections in hamsters be administered (4)?

Jugular vein, cephalic vein, tarsal vein, and lingual vein.

When can simple blood sampling be accomplished with hamsters?

When they are awake and restrained.

What disease in hamsters causes profuse watery diarrhea, lethargy, weight loss, depression, irritability, rectal prolapse, anorexia, and sudden death?

Wet tail

What is the causative agent of wet tail in hamsters?

It is unknown.

Hamsters may be more susceptible to_________ than other rodents.

Salmonella

_____________ disease is not commonly seen in hamsters but may be due to lack of diagnosis because clinical signs are similar to wet tail.

Tyzzer's

What are the clinical signs of salmonella in hamsters?

Lethargy, rough coat, weight loss, distended abdomen, and increased respiration rate.

Lymphocytic choriomeningitis virus is a zoonotic disease that causes ___________ in humans.

Meningitis

What are the clinical signs of lymphocytic choriomeningitis virus in hamsters?

Asymptomatic

What do hamsters have a sensitivity to?

Antbiotics

What kind of dwellers are gerbils?

Desert dwellers

What are gerbils incredibly driven to do?

Burrow

What are Some strains of gerbils susceptible to have?

Epileptiform seizures

For gerbils, the relative humidity in labs should be________ than other lab animals.

Lower

Gerbils have a low to moderate requirement for what?

Water

Gerbils have very little __________ output.

Urine

Gerbils are

Nonaggressive

How aggressive are they?

What kind of bedding to gerbils have a sensitivity to?

Cedar

You should avoid turning gerbils over on their _______.

Backs

Gerbils are __________ and will mate for life.

Monogamous

Where are Intraperitoneal injections administered in gerbils?

Lower right or left quadrant

Where should Intravenous injections be administered in gerbils?

Lateral tail vein

What is nasal dermatitis (sore nose) caused by in gerbils?

High stress and anxiety

Gerbils alleviate stress by

Excessive burrowing

Why do gerbils need regular teeth trimmings?

Prevent maloclusions and overgrowth of inscisors

What is the rabbit classified as?

A lagomorph of the family leporidae

What is the most common specific pathogen free (SPF) rabbit produced commercially for research?

New Zealand white rabbit

When are rabbits most active?

At twilight (crepuscular)

How do rabbits act when they are handled roughly?

They may vocalize with a high pitch scream

What should rabbits be fed?

A pelleted high fiber rabbit diet and supplemented with good quality grass hay

What is the advantage of rabbit's ears?

They are highly vascular allowing for easy intravenous and intraarterial access

How many inscisors do rabbits have?

2 upper pairs

What kind of teeth do rabbits have?

Open rooted teeth

If rabbits teeth are not naturally worn down, what needs to happen?

They need to be trimmed.

If rabbit teeth are not trimmed, what health conditions can occur?

Maloclusion

What is cecotroph?

Night feces that are moist, strong in odor, bright green, and mucus covered.

What do rabbits do with cecotroph?

They eat it directly from anus

What area of the rabbit should they never be picked up at?

Ears

What kind of ovulators are rabbits?

Induced ovulators

Since rabbits don't have a estrus cycle, what do they have?

A period of receptivity that lasts between 7 and 10 days.

If nasogastric tubes are neccessary in rabbits, what is recommended after the tube is placed?

Radiograph

When saline is introduced in a rabbits body, they will not ________ if it is introduced directly into the lungs.

Cough

What kind of injection is not recommended in a rabbit?

Intraperitoneal

For IV injections in a rabbit, what veins are used (3)?

Marginal ear vein, saphenous vein, and cephalic vein.

For IM injections in a rabbit, what muscle locations are used (2)?

Inner thigh muscle or lumbar muscle

For SQ injections in a rabbit, what areas are used (3)?

Area of scruff behind the neck, over the shoulder, over the flank

What is the major causative agent in snuffles or upper respitory tract infections in rabbits?

Pasteurellosis

What causes clinical presentations of upper respitory infections, otitis, pleuropneumonia, bacteremia, and abscesses in rabbits?

Pasteurellosis

What causes clinical signs of nasal discharge, ocular discharge, dermatitis, torticollis, vaginal dishcharge, and abscess formation in rabbits?

Pasteurellosis

What is the disease called that causes hairballs in rabbits?

Trichobezoars

What causes trichobezoars (hair balls)?

A diet low in fiber

What are the two forms of coccidiosis?

Hepatic or intestinal

What health condition causes clinical signs of diarrhea and possible death in case of heavy infection?

Intestinal coccidiosis

What causes clinical signs of diarrhea, abdominal swelling, weight loss, anorexia, icterus, and sudden death in rabbits?

Hepatic coccidiosis

What disease is caused by a number of agents like fur and ear mites, dermatophytes, maloclusions, and possibly barbering in rabbits?

Dermatitis/alopecia

What disease in rabbits is caused by fly larvae?

Cuterebriasis

What kind of rabbits does cuterebriasis usually occur in?

Pet or breeding rabbits

What are the most common strains of guinea pigs (3)?

Peruvian (lomghaired), Abyssinian, and English short haired.

What type of vitamin needs to be provided In guinea pig diets?

Vitamin c

How many nipples do guinea pigs have?

2

When should guinea pigs be bred?

Before 6 months of age

During the later stages of pregnancy in guinea pigs, adequate _______ should be given when handled.

Support

What is the gestation of a guinea pig?

63 days

Describe newborn guinea pigs.

Precocious and relatively mature with hair, erupted teeth, and open eyes

Guinea pigs have very ______skin.

Tough

What veins are used in IV injections in guinea pigs(4)?

Marginal ear vein, saphenous vein, cephalic vein, and penile vein.

What disease causes clinical signs of lameness, rough coat, weight loss, change in teeth and gums, nasal and ocular discharge, and effected limbs and joints in guinea pigs?

Scurvy (hypovitaminosis C)

What disease causes the intestinal flora in guinea pigs to be drastically altered leading to an overgrowth of gram negative organisms?

Antibiotic associated enterotoxemia

What teeth do guinea pigs have more problems with?

Premolars and molars

What health condition causes clinical signs of the "slobbers" in guinea pigs?

Maloclusions

The bacteria streptococcus causes what in guinea pigs?

Cervical lympadenitis (lumps)

Why is cervical lymphadenitis easily recongnizable?

Because the cervical masses contain pus

Where do chinchilla come from?

South America

What kind of research are chinchillas used for?

Hearing

What do chinchillas require daily to every other day?

Dust baths

What Is unique about chinchilla fur?

It is extremely luxurious and contains more fur per square inch than any other animal

Are chinchillas caprophagic?

Yes

What can rough or inexperienced handling cause in chinchillas?

Fur slips

How are chinchilla babies born?

Precocious with teeth and open eyes and ears

What kind of medications are chinchillas sensitive to?

Injectable meds

What kind of medications should be given to chinchillas?

Oral

What can't chinchillas do?

Vomit

What health condition causes clinical signs of retching, drooling, dyspnea, and anorexia?

Choke and bloat

How do chinchillas lay when they have choke and bloat?

On their sides

What disease can chinchillas get that causes hairballs?

Trichobezoars

What is caused by a ring of fur around the penis in chinchillas?

Fur ring and paraphimosis

What can African clawed frogs generate if lost?

Limbs

What should be avoided when handling African clawed frogs?

Disruption of its protective layer of mucus

What can induce health and distress in African clawed frogs?

Environmental stresses

What health condition is caused by a bacterial infection in African clawed frogs?

Red leg

Red leg causes high _______ and ______ in African clawed frogs.

Morbidity and mortality

What health condition shows Clinical signs of hemorrhage in extermeties in African clawed frogs?

Red leg

What health condition is characterized by subcutaneous fluid accumulation in African clawed frogs?

Dropsy or bloat

Parrots, cockatoos, macaws, budgies, and cockatiels are what class of avians?

Psittaformes

Finches, canaries, and mynahs are what class of avians?

Passeriformes

What vein in the neck is used for blood collection in birds?

Right jugular vein

What 2 veins are used in a bird's wing for blood collection?

Brachioulnar vein or cutaneous ulnar vein

What 2 veins are used for blood collection in a bird's leg?

Medial tibiotarsal or medial metatarsal veins

Where are IV catheters placed in birds?

Wing or leg veins

Where are intraosseous catheters placed in birds?

Proximal tibia or distal ulna

What muscle is IM injections typically used in birds?

Pectoral muscle

What is used to cauterize a bird's beak after trimming?

Hemostatic powder

What feathers should be checked before trimming?

Blood feathers

What health condition in birds can cause abdominal distention, dyspnea, and hypocalcemic seizures?

Egg binding

What health condition is caused by courtship behavior, lead poisoning, foreign body ingestion, and gastrointestinal problems?

Regurgitating/vomiting

What dietary deficiency in birds is caused by not enough vitamin A in the diet which causes unhealthy mucous membranesan epithelium?

Hypovitaminosis A

What dietary deficiency in birds is caused by not enough calcium from egg binding and metabolic bone disease?

Hypocalcemia

What kind of toxins can be harmful to birds?

Inhalants from household appliances or products, paints, and pesticides.

What classification of reptiles are turtles and tortoises in?

Chelonia

What classification of reptiles are crocodiles, alligators, and caimans in?

Crocodilia

What classification of reptiles are snakes in?

Serpentes

What classification of reptiles are lizards in?

Sauria

Why is taking temperatures of reptiles not useful?

Reptiles are ectothermic

What spots can blood be collected from in lizards and chelonians?

Ventral tail vein

What spots can blood be collected from in snakes?

Dorsal and ventral buccal veins of the mouth

What two areas in mouth

What spots can blood be collected from in chelonians?

Right jugular vein and dorsal venous sinus of tail

Where can IV injections be injected in chelonians?

Right jugular or cocccygeal vein

What spot can IV injections be injected in lizards?

Ventral abdominal or tail vein

Where can IV injections be injected in snakes?

Coccygeal or right jugular vein

Where should IM injections in chelonians and lizards take place?

Front legs

Where should IM injections in snakes take place?

Dorsal spacial muscles in cranial half

What disease is common in green iguanas and chameleons?

Metabolic bone disease (hypocalcemia)

What disease comes with clinical signs such as fractures of long bones, thickened and swollen jaws and thing he in reptiles?

Hypocalcemia

Where are prairie dogs native to?

North America and the great plains

Why do prairie dogs require a large amount of roughage in their diet?

They are hind gut fermenters

Prairie dogs are susceptible to what type of diseases?

Zoonotic

Prairie dogs can be carrier's and serve and a reservoir for what disease?

Yersinia pestis

How is yersinia pestis transmitted in prairie dogs?

Through flea bites

What disease in prairie dogs causes lethargy, anorexia, depression, respitory distress, and lymphoadenopathy?

Yersinia pestis

What virus caused a ban on the sale, transport, and display of prairie dogs in 2003?

Monkeypox virus

What kind of tails do spiny mice have?

Scaled tales

What kind of animals are sugar gliders?

Marsupials

What does a female sugar gliders well developed pouch contain?

4 teats

What kind of opening do sugar gliders have in the caudal end?

Cloacas

What disease in sugar gliders cause diarrhea, anorexia, rectal prolapse, and constipation?

Gastrointestinal disease

What are aggressive, biting and eating disorders called in sugar gliders?

Polyphagia/polydipsia

These clinical symptoms cause what kind of disease in a sugar glider: coughing, wheezing, lethargy, dyspnea, increased lung sounds, inapetance, and nasal discharge?

Respitory disease

What disease in sugar gliders causes lethargy,weakness, hind limb paralysis, hypothermia, tremors, ataxia, fractures, and seizures?

Metabolic bone disease (hypocalcemia)

What are male ferrets called?

Hobs

What are female ferrets called?

Jills

What are castrated male ferrets called?

Hobbles or gibs

What are spayed female ferrets called?

Sprites

What are young ferrets called?

Kits

What disease in ferrets causes symmetrical alopecia, muscle atrophy, pruritus, vulvar enlargement in females, increased aggression and musky odor, and prostatis in males?

Hyperadrenocorticism (adrenal disease)

What disease in ferrets causes anorexia, weight loss, lethargy, and palpable lymph nodes or nodules on liver and spleen?

Lymphoma

What disease in ferrets causes episodic signs of weakness, ataxia, seizures, and sudden collapse with frequent recovery?

Insulinoma

What are the most common insulin secreting tumors in ferrets?

Neoplasia

What human viruses are ferrets susceptible to?

Human influenza

What disease in ferrets cause swollen vulva, alopecia, petechial hemorage, anorexia, pale mucous membranes, and marked depression?

Aplastic anemia

Female ferrets that are not bred and undergo prolonged periods of estrus contribute to what disease?

Aplastic anemia

What kind of mites are ferrets susceptible to?

Fleas, heartworms, ear mites, and sarcoptic mange