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64 Cards in this Set
- Front
- Back
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Angioedema
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minor Recurrent Aphthous Stomatitis
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Major RAS
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Herpetiform RAS
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Behçets disease
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Lichen planus
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Systemic lupus erythematosus (SLE)
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Erythema multiforme
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Orofacial granulomatosus
Oral menifestions of Crohn's disease |
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Mucous membrane pemphigoid
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Pemphigus vulgaris
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Systemic sclerosis
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angioedema
What is it? |
Recurring, rapid swelling of the lips and adjacent
structures in susceptible patients after contact with an allergen |
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angioedema
Types? Which is more common? |
Acquired is more common
Hereditary |
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angioedema
some drugs that cause it? |
ACE inhibitors
NSAIDs (aspirin and indomethacin) Carbamazepine Cephalosporins Iodine - contrast media Barbiturates Food (egg, nuts, chocolate, fish, strawberries etc.) |
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Recurrent aphthous stomatitis
sex and age? |
females
children above 5 |
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Recurrent aphthous stomatitis
types? which one's majority? |
minor (majority)
major herpetiforme |
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Recurrent aphthous stomatitis
aetiology/ |
Genetic
immunodeficiency/stress/Psychological trauma deficiency in iron, VB12, folate allergy hormone HIV Sessation of smoking |
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Recurrent aphthous stomatitis
Smokers are Risk group? T/F? |
False
non-smokers |
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Recurrent aphthous stomatitis
Recurrent in children? T/F? |
No
begin in childhood recurrent in adults |
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Minor Recurrent aphthous stomatitis
site? numbers? size? scarring? healing? |
non-keratinised epithelium
2-5 ulcers < 1cm no scarring healing takes within 14 days |
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Major Recurrent aphthous stomatitis
site? size? number? healing? scarring? |
keratinised and non-keratinised epithelium
1-2 cm 1-2 ulcers takes 14 days or more leaves scar |
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HerpetiformRAS
incidence site number size healing scarring |
10%
keratinised and non-keratinised epithelium several small ulcers small 1-2mm 1 to 6 months may leave a scar |
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HerpetiformRAS
is it recurrent? |
yes
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Behçets disease
it is prevalent in Caucasian T/F? |
false
Turkey and Japan (silk road) |
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Behçets disease
sex? |
males
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Behçets disease
clinical features? |
oral/genital ulcers
occular uveitis and blindness skin pustules, erythema nodusum joint arthraliga vascular aneurisms, thrombosis renal: proteinuria and haematuria Neuropsychiatric: similar to multiple sclerosis |
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Behçets disease
How to diagnose it? |
Recurrent oral ulcers
AND Two of the following: Recurrent genital ulcers Eye lesions Skin lesions Positive pathergy test |
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Oral lichenoid reaction
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Oral lichenoid reaction
aetiology? |
Exposure to dental resto material
Chronic GVHD HepC V Drugs: antihypertensive, NSAIDS |
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Oral lichenoid reaction
with Hypertension and diabetes is called.. |
Grinspan syndrome
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Lichen planus
frequency? |
common
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Lichen planus
uni-lateral or bilateral? |
bilateral
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Lichen planus
location |
buccal and lingual mucosa and gingiva
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Lichen planus
cause? |
due to drug therapy
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Lichen planus
what are the types? |
reticular
plaque like papular erosive ulcerative bullous |
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Lichen planus
what's its prognosis toward malignancy? |
less than 1%
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Lupus erythematosus
frequency? |
uncommon
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Lupus erythematosus
What are the types? Differentiate |
Discoid: single isolated
Systemic: widespread to other parts of the body |
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Systemic lupus erythematosus (SLE)
oral menifestation? |
similar to DLE
more ulcerations Sjogren syndrome |
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Lupus erythematosus
Prognosis towareds malignancy? |
Maybe for DLE
No for SLE |
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Lupus erythematosus
cause? |
idiopathic
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Lupus erythematosus
sex and age? |
adult females
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Lupus erythematosus
oral lesion location and laterality |
Bilateral
buccal mucosa/gingiva/lip/vermillion |
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Erythema multiforme
aetiology? |
not clear
maybe organisms such as HSV disorder eg hepatitis BCG drugs eg ABiotics |
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Erythema multiforme
oral manifestation? |
Diffuse widespread macules to blisters and ulceration
Swollen and cracked lips with bleeding and crust formation Pronounced lesions on the non-keratinised mucosae |
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Erythema multiforme
Recurrence? |
weeks to years, attacks last for 10-20 days once or twice a year
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Orofacial granulomatosis
Orofacial features? |
facial / labial / gingival swelling
angular cheilitis cracked lips mucosal tags cobble-stoning CLN enlargement |
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Crohn's disease
Orofacial features? |
Swellings of the lips
Angular cheilitis Oral ulcers Gingival swellings Mucosal tags Folding of mucosa (cobblestone appearance) |
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Mucoud membrane pemphigoid (MMP)
Frequency |
Uncommon,
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Mucoud membrane pemphigoid (MMP)
What is it? |
autoimmune disease characterised by damages to hemidesmosomes of basement membrane.
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Mucoud membrane pemphigoid (MMP)
sex? |
females
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Mucous membrane pemphigoid (MMP)
predisposing factors? |
genetic
drugs: furosemide and penicillamine |
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Mucoud membrane pemphigoid (MMP)
Oral features: |
erythema, vesicle, bullae, blood filled blisters, ulcer,
desquamative gingivitis |
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Pemphigus vulgaris (PV)
what is it? |
Rare autoimmune disease affecting middle aged
from Ashkenazi Jewish, Asian and Mediterranean descent Auto-antibodies against desmoglein targeting desmosomes of epithial cells |
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Pemphigus vulgaris (PV)
sex? |
females
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Pemphigus vulgaris (PV)
Predisposing factors:? |
genetic
drugs radiation |
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Pemphigus vulgaris
clinical features? |
Blisters and scabs on the skin
Erosions and ulcers of the mucosae of oral cavity, conjunctiva, nasal cavity, pharynx, larynx, oesophagus, rectum, genitals Blisters are thin and easily ruptured |
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Pemphigus vulgaris
locations? |
palate, buccal mucosa, lips, gingiva
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Systemic sclerosis
what is it? |
Generalised condition characterised by replacement of the normal connective tissue with dense collagen resulting in fibrosis, loss of mobility and organ dysfunction
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Systemic sclerosis
FEATURES (CREST) |
Calcinosis
Raynaud phenomenon Oesophageal strictures Sclerodactyly Talengiectasia |
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Scleroderma:
orofacial features? |
Progressive restriction of mouth opening
Xerostomia (dryness of the mouth) Dysphagia due to oesophageal involvemnent Generalised induration of mucosa Tongue changes Periodontitis Temporomandibular joint dysfunction, pain Cortical erosion of mandible |
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Differentiate between Orofacial granulomatosis and Crohn's disease
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OFG has similar orofacial features as Crohn's but without association with any systemic disorder
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Differentiate between Systemic lupus erythematosus and Discoid lupus erythematosus
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Systemic: more severe. Targets kidneys. Butterfly rash.
Discoid: less severe. Affects orofacial regions only. Scalp, face, oral mucosa, ears |