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20 Cards in this Set
- Front
- Back
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What does staining with MPO indicate?
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Granulocytes
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What does staining with NSE indicate?
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Monocytes
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What does staining with PAS indicate?
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Erythrocytes and lymphocytes
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Leukemia:
t(15;17) |
Promyelocytic
PML-RAR - treat with ATRA |
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Leukemia t(8;21)
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Myeloblastic w/maturation
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Leukemia:
inv(16) |
Myelomonocytic
Also gum involvement |
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Markers for B cell ALL
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CD19, CD20, CD10 (CALLA), HLADR-
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Markers for T cell ALL
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CD2, CD3, CD7
(CD2 is also seen in APML) |
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What translocations are commonly seen in B-ALL?
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t(8;14)
t(1;19) t(9;22) - worse prognosis t(8;22) t(2;8) t(4;11) - bad - also biphenotypic AML t(17;19) |
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What translocations are commonly seen in T-ALL?
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t(11;14), t(1;14), t(10;14)
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Lymphoma:
Trisomy 12 Del 13q14 Del 11q22-23 |
SLL/CLL
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Lymphoma:
CD19, 20, 5, 23+ |
SLL/CLL
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Lymphoma
t(11;14) |
Mantle Cell Lymphoma (worst prognosis)
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Lymphoma
CD23- |
MCL
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Lymphoma
t(14;18) |
Follicular Lymphoma
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Back to back follicular growth, no white spaces, centroblasts and centrocytes
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Follicular Lymphoma
t(14;18) |
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Lymphoma
t(11;18), Trisomy 3 |
Marginal Zone Lymphoma (MALToma)
Does not respond to abx when there is this abnormality) |
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Lymphoma
t(8;14) |
Burkitt's
Starry sky appearance Associated with EBV, jaw lesion |
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Lymphoma:
Loss of CD2, 3, 5, 7 |
Peripheral T cell lymphoma
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Lymphoma:
t(2;5) |
Anaplastic Large Cell Lymphoma
Stains for ALK protein |
