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17 Cards in this Set

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NPC1L1

Cholesterol transport protein on apical membrane of enterocyte

Niemann Pick

CD36

Fatty acid transport protein on apical membrane of enterocyte

FABP

Fatty acid binding protein; transport FA to ER

FATP/acyl-coa synthase

Adds acyl coa to fatty acids

ACAT, MGAT, DGAT

Esterifies fatty acids or cholesterol

MCT

Microsomal triacylglycerol transport protein, adds apo B48 to form chylomicrons

ABCA1

ATP-binding cassette protein-fxns in liver, SI. Interacts with apoA-1 to create HDL. Absence of ABCA1-Tangiers disease.

ApoA-1


LCAT

Lecithin cholesterol acyltransferase, involved in HDL maturation

HDL

PLTP

Phospholipid transfer protein

HDL maturation

CETP

Cholesterol ester transfer protein

HDL maturation

ABCG1

forms an heterodimer; mediates transfer of cholesterol to mature HDL. Found on macrophages

Macrophages

SREBP

Induces fatty acid and cholesterol formation

Opposed by Omega 3

Enteropeptidase

Enzyme that activates tripsinogen to tripsinogen, as well as activating other enzymes involved in peptide digestion


Tripsin inhibitor

Protease inhibitor that affects protein quality/digestibility


Stearic acid

18:0

Palmitic acid

16:0

Trypsin activates

Colipase to lipase