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60 Cards in this Set
- Front
- Back
whats does the lymphatic system do
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defends the body
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what does the lymphatic system contain
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cells, tissues, and organs
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what does lymphocytes do
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resist infection and disease
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primary function of the lymphatic system
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production, maintenance, and distribution of lymphocytes
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color of lymph and compare to what
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clear, colorless, like plasma with less proteins
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lymphatic vessels are closed in
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one end
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what is tethered to surrounding tissue
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protein filaments
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ENDOTHELIAL CELLS LOOSELY
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OVERLAPPED
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how many classes of lymphocytes
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Three, T, B, NK
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T
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thymus dependent
80% |
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B
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(bone marrow-derived) cells ( 15% )
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NK
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(natural killer) cells ( 5% )
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Lymphocyte production
Involves |
bone marrow, thymus, and peripheral lymphoid tissue
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B cells and NK cells mature in
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bone marrow
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T cells mature in the
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thymus
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Connective tissue dominated by lymphocytes
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LYMPHOID TISSUE
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Lymphocytes densely packed in areolar tissue
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Lymphoid nodules
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Lymphoid nodules
Found in the |
respiratory, digestive, and urinary tracts
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MALT
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(mucosa-associated lymphoid tissue)
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Collection of lymphoid tissues linked with the digestive system
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MALT
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function in the purification of lymph ( Filter the lymph )
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LYMPH NODES
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carry lymph to nodes
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Afferent lymphatics
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carry lymph from nodes
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Efferent lymphatics
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Deep cortex dominated by
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T cells
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Outer cortex and medulla contains
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B cells
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THE THYMUS
Located |
behind sternum in anterior mediastinum
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Capsule
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THE THYMUS
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Two lobes
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THE THYMUS
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Divided into lobules, each with a cortex and medulla
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THYMUS lobes
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Cortical lymphocytes surrounded by
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reticular endothelial cells
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thymus barrier
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Maintain blood
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Secretes thymic hormones
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THYMUS
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thymosins, thymopoietins, and thymulin
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thymic hormones
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Largest mass of lymphoid tissue
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THE SPLEEN
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Cellular components form
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pulp
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Red pulp contains
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RBC
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White pulp similar to
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lymphoid nodules
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Removal of abnormal blood cells and other blood components
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THE SPLEEN
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Storage of iron
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THE SPLEEN
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Initiation of the specific immune response (Filters the blood, Quick to detect antigens )
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THE SPLEEN
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broadly effective, no prior exposure.
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NONSPECIFIC DEFENSES
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protect against particular threats, depend upon the activation of lymphocytes
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SPECIFIC DEFENSES
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Keep hazardous organisms outside the body
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PHYSICAL BARRIERS
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Includes hair, epithelia, secretions of Integumentary and digestive systems
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PHYSICAL BARRIERS
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Remove cellular debris and respond to invasion by foreign pathogens
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PHAGOCYTES
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Fixed and free
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Monocyte-macrophage system
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Move by diapedesis
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PHAGOCYTES
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Exhibit chemotaxis
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PHAGOCYTES
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Constant monitoring of normal tissue by NK cells
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IMMUNOLOGICAL SURVEILLANCE
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Recognize cell surface markers on foreign cells
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NK cells
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Destroy cells with foreign antigens
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NK cells
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cytokines
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INTERFERON
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Small proteins released by virally infected cells
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INTERFERON ( cytokines )
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Trigger the production of antiviral proteins
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INTERFERON ( cytokines )
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Three major types of interferons are:
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Alpha
Beta Gamma |
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produced by leukocytes and attract/stimulate NK cells
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Alpha
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secreted by fibroblasts causing slow inflammation
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Beta
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secreted by T cells and NK cells stimulate macrophage activity
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Gamma
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Cascade of 11 plasma complement proteins (C)
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COMPLEMENT SYSTEM
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Destroy target cell membranes
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COMPLEMENT SYSTEM
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