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43 Cards in this Set
- Front
- Back
Methacholine |
Diagnosis of Bronchospasms |
|
Carbachol
|
glaucoma Eye Surgery |
|
Bethanechol
|
urinary retention and atony of muscles |
|
Pilocarpine
|
0.5% solution in treatment of Glaucoma
muscuranic-specific
S.E.: sweating, salivation & gastric secretion |
|
physostigmine
|
Glaucoma Treat overdoses of anticholinergics Investigational in Alzheimers
|
|
neostigmine
|
Post surgical atony of muscles improve myasthenia gravis, ptosis and diplopia
longer DOA than Physostigmine not affected by pH |
|
Pyridostigmine |
Tx of myasthenia gravis
1/5th as toxic as Neostigmine
|
|
edrophonium |
Diagnosis of myasthenia gravis |
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ambenonium |
Tx of Myasthenia Gravis (alternative to neostigmine or pyridostigmine) |
|
demacarium
|
Tx of open/wide angle glaucoma |
|
tacrine
|
Alzheimer's |
|
donepezil
|
Alzheimer's; dementia |
|
rivastigmine
|
Alzheimer's |
|
Isofluorophate |
Glaucoma |
|
echothiophate |
Glaucoma |
|
atropine |
Mydriatic/cycloplegic agent duration refraction studies in iritis and uveitis
suppress toxicity from organophosphate |
|
scopolamine |
Motion sickness |
|
Homatropine
|
Mydriatic/cycloplegic property |
|
ipratropium
|
Asthma, COPD |
|
Tiotropium |
Asthma, COPD |
|
Clidinium |
Antispasmodic & antisecretory
with chlordiazepoxide (tranquilizer) for peptic ulcer and GI secretory disease |
|
Dicyclomine |
antispasmodic effect on GIT smooth muscle irritable bowel syndrome
affinity for M1 and M3 > M2 & M4 |
|
Glycopyrrolate |
Hyperhidrosis and sialorrhea
with Neostigmine to balance heart rate
asthma &COPD
affinity for M1 > M2 & M3
In high doses, can block gang. & NMJ receptors |
|
Propantheline |
Antispasmodic & antisecretory |
|
Diphenhydramine |
Antihistaminic agent; allergies
alleviates some PD symptoms
S.E: drowsiness & CNS depression |
|
Benztropine |
Management of PD
minimizes sialorrhea, oculogyric crisis & muscular cramps
as potent as atropine
|
|
Biperiden |
Useful for idiopathic and induced PD
alleviates akinesia, rigidity and tremors
spastic disorder e.g. spinal cord injury, cerebral palsy & multiple sclerosis
more affinity for M1 |
|
Procyclidine |
improves rigidity or bradykinesia |
|
Trihexyphenidyl |
All forms PD
reduces mydriasis and sialorrhea
Binds M1
half of atropine's potency - safe! |
|
Isopropamide |
peptic ulcers
long DOA |
|
Darifenacin |
antidiuretic
M3 selective |
|
Ethopropazine |
PD; antidyskinetic
improves tremors, sialorrhea, rigidity & oculogyric crisis |
|
Papaverine |
Raynaud's Disease
lacks potency
inhibits hydrolisis of cAMP & cGMP
|
|
Nicotine |
Stimulant at low dose
Gang. Blocker @ high dose |
|
Hexamethonium |
Hypertension
strong gang. blocker; weak curariform activity
|
|
Decamethonium |
Hypertension
Weak gang. blocker; strong curariform activity |
|
Trimethaphan |
Hypertension
administered by IV |
|
Mecamylamine |
Hypertension
absorbed in GIT
Both comp. and non-comp. inhibitor
S.E. orthostatic hyprtension
|
|
Tubocurarine |
Adjunct in gen. anesthesia
administered by IV
reversed by neostigmine and edrophonium |
|
Atracurium |
skeletal muscle relaxant for short surg. procedures
2.5X as potent as tubocurarine
reversed by pyridostigmine, neostigmine and edrophonium |
|
Doxacurium |
skeletal muscle relaxant surg. procedures > 90 mins |
|
Pancuronium |
skeletal muscle relaxant DURING surgery
Effect increased by gen. anestetics
acts on nicotinic receptor and in ion channel
5X as potent as tubocurarine |
|
Succinyl |
skeletal muscle relaxant DURING surgery
used in intratracheal intubation and endoscopic procedures
unstable in alkaline solution (should not be mixed with thiopental sodium)
Effect not reversed by AChE inhibitors |