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17 Cards in this Set
- Front
- Back
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Wandering or free phagocytes Granulocytes |
Neutrophils Eosinophils Basophils |
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Wandering or free phagocytes Agranulocytes |
Monocytes
Lymphocytes-antibody production or humoral defence |
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Neutrophils |
60-70% of total wbc Very phagoctic 1st wbc at infection Scavenger cell Granules (lysozyme and lactoferrin)
Leukocytosis: acute infections and neutrophilia Leukopenia/neutropenia |
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Eosinophils |
Pink color 2-4% of total WBC Some phagocytic activity Role in allergies (hypersensitivity) Granules (histamine 1/3 blood supply) Eosinophilia:allergies and parasitic infection |
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Basophils
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0.5-1% of WBC
Purple
Some phagocytic activity Important role in graft regection And viral immunity
Granules: Heparin (blood thinner) Seratonin (vasodialation) vsjsbsbsns Histomine (1/2 blood supply) |
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Monocytes |
2-8% of WBC Largest WBC: 10-20 MICRONS Not phagocytlc while in blood but a macrophage when it enters tissue Monocytosis: Certain bacterial infections (TB, Rickettsial Infections), protozoa and fungal infections |
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Types of phagocytic cells |
Aveolar macrophages (lungs) Kupffer cells (liver) Lymphocytic macrophages (lymphnodes) Microglial cells (brain CNS) Osteoclasts: bones |
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Inflammatory response |
Sum of rxn In the body incited by injury |
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Vasodialation |
· Increase in vascular permeabllity, increase in blood flow from capillaries to damaged tissue, edema (Swelling), redness, warmth · Types: Bradykin, kinin, histamine (Eoslnophils & basophils), and serotonin (Platelets & basophils) |
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Hemostatic plug |
Fibrin clot wall off |
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Pus formation |
Dead cells and body fluid |
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Chemotaxis |
Phagocytes move to injured area |
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Margination |
WBC cling to lining of blood vessels |
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Diapedesis |
Phagocytic WBC move from blood tissue Fever incites the process takes only 2 minutes |
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General body rxn 7-10 pg 10 |
7 Neutrophils 4-5 fold increase (first arive within hour) 8 monocytes arive in 12 hours Enter tissue and become macrophages 9 Eosinophils and basophils apear 10 antibodies formation |
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Tissue repair |
Fibrinolysis plasminogen converted to plasmin which breakes down fibrin clot
Fibroblasts: forms scar tissue |
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General body rxn 1-6 |
1 Vasodialtion 2 Hemostatic plug 3 pus forms 4 chemotaxis 5 margination 6 diapedesis |
