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98 Cards in this Set

  • Front
  • Back

Plasma is a mixture of _______ and _________.

ionized gas


free-floating electrons

SI standardized units of measure based on the metric system 7


length


mass


time


electric current


temp


luminous intensity


amount substance

m


Kg


s second


A ampere


K


cd candela


mol mole

12 standard prefixes of naming units of measure to denote quantity

T


G


M


k


h


da


d


c


m


u


n


p



periodic table of elements


vertical columns =

groups have similar properties

horizontal rows

periods

Neil Bohr discovered what about electrons

described electron orbits in terms of energy levels and ability to emit quantized energy by stimulated emission

atomic theory describes what about atoms

atoms have a central core, the nucleus, with orbiting particles called electrons.



nucleus contains

protons and neutrons


p=+


n= 0


e = -



atomic number define

the number of protons in an atoms

ions define

are atoms that have gained or lost electrons from their natural composition



atom gained electron=

anion

atom lost electron =

cation

isotopes define

the same elements have the same number of protons but different numbers of neutrons. isotopes of the same element have differing mass numbers.

molecules define

two or more bonded atoms

valence electrons define

electrons in the outermost shell and involved in bonding

covalent bond define

physical sharing of electrons between atoms


happens between same or different atoms that share similar electronegativity

2 general types of bonds


which is stronger

covalent*


electrostatic

electrostatic bonds define

are made by attraction of electrons between atoms

3 types of electroatatic bonding, ex, strongest

ion-ion* NaCl


ion-dipole H2O + Na


dipole-dipole H2O

some molecules have induced dipoles caused by momentary uneven spatial distribution of electrons. induced dipoles are not permanent. Lead to weak bonding between nonpolar molecules called ______

london dispersion forces - are the weakest of all molecular bonds

isomers define


isomers may be structural or stereoisomers

are molecules that have the same chemical formula but different structural formulas.

structural isomers define

have the same molecular formula but their atoms are located in different places


ex isoflurane and enflurane


have different physical and chemical properties

stereoisomers

define

are molecules that have similar geometric arrangement of atoms but differ in their spatial position may be enantiomers or diastereomers

enantiomers

are mirror images of one another, cannot be be superimposed, and posses similar chemical and physical properties.

bond energy define

is the amount of energy needed to make or break a bond

forming a bond (needs energy or release energy)

release energy

enthalpy define

is the total amount of energy possessed by a system. total kinetic and potential energy.

organic chemistry is the study of _____ containing molecules

carbon

single bonded carbon chains are called


double or triple bonded carbon chains

saturated hydrocarbons


unsaturated

single bonds


double bonds


triple bonds


alkanes


alkenes


alkynes

NR3


ROH


ROH ring


ROR'


RCHO


RCOR'


RCOOH


RCOOR


RCONH2

amines


alochols


phenols


ether


aldehyde


ketones


carboxylic acid


esters


amides

hypothermic patients receiving voliate agent increase or decrease solubility of the gas

increase solubility less kenetic energy when it is cold. so gas diffuses into a liquid at a greater extent.

p=kc


henry's law

henry's law (gas solubility) at a constant temp. the amount of gas dissolved in a liquid is directly proportional to the partial pressure of that gas at equilibrium above the gas-liquid interface

how does henry's law relate to delivering anesthetic gas, what phenomena

overpressurizing - is the process of significantly increasing a volatile anesthetic concentration (partial pressure) delivered to a patient increase the alveolar concentration and therefore the amount dissolved in the blood, to speed uptake

diffusion

is the process of net movement of one type of molecule through space as a result of random motion intended to minimize a concentration gradient

r=1/✓mw


Graham's law


how does this relate to diffusion of gas

graham's law determines the faster diffusion of smaller molecules compared to larger molecules

osmosis

movement of water across a semipermeable membrane to equilibrate a concentration gradient

osmotic pressure vs oncotic pressure

osmotic pressure is the force needed to stop osmosis from occuring. oncotic pressure is the osmotic pressure by plamsma proteins and electrolytes in capillaries.

what opposes oncotic pressure

hydrostatic pressure tendency to push water out of the capillaries

normal oncotic pressure =

28 mmhg

diffusion of anesthesia - the continual diffusion of 02 into the blood is driven by a concentration gradient that continuously diffuses o2 into the alveoli via the ventilator circuit




what law

fick's law diffusion of gas across biological tissues

Fick's law explains what phenomena

diffuision hypoxia - the stopping of N20 and not increasing fio2 of O2.

fick formula

J=⍺D/ △ x (Pao2 - Pcapo2)

Mass vs weight

mass is the total of all matter in an object (p,e,n), weight total effect of gravity pulling on (p,e,n)

gravity = ?? amount

9.81m/sec2

gravitational force = ?? formula

gravitional force = (Gxm1xm2)/(d

a feather and a rock will fall to the earth at the same speed why and what law?

3rd law of motion - objects resist movement proportional to their mass


greater pulling but also greater resistance

newtons 3 laws of motion


1. law of inertia


2. law of acceleration


3 law of reciprocal action

1. a body in motion stays in motion unless acted upon by another force


2. acceleration of a body is in the direction of and proportional to the sum of all the forces called vectors


3. for every action there is an equal and opposite reaction.

F=ma


standard unit

force=mass x acceleration


measured in newtons

PVR = ?? normal values


SVR = ?? formula

100-200 dyne sec/cm5


900-1200




SVR= (MAP-CVP) / CO

normal axis of electrical flow summation of vectors n the heart is

-30 to +90 degrees

draw axis deviation vector

???

standard unit of measurement for pressure

pascal (Pa)

P=f/a


Pa=1N/1m^2


1N = 102 grams

??

difference in pressure applied to TB syringe and 10ml syringe which creates greater force

TB syringe will have greater pressure that is why you de-clog catheters will larger syringes, you can rupture the catheter

atmospheric pressure is the column of gravitational force on gases over a given area

100kPa or 760mmHg or 1020 cm H20 or 14.7 lb/inch^2

1 torr= ___ mmHg


1kPa = _____cm H20 = _____ mmHg


1 atm = ____ mmHg = ____ torr = ___bar = _____kPa = _____cm H20 = _____ lb/inch^2

1


10.2, 7.5


760, 760, 1, 100, 1020, 14.7

what does manometer measure

is a liquid-filled tube that is open to atmospheric pressure on one end and exposed to a pressure for measurement on the other end. it measures pressure in a tube.

give an example of a real life manometer we use everyday

sphygmomanometer BP cuff

absolute pressure =

atmospheric pressure + gauge pressure

gauge pressure=

absolute pressure - atmospheric pressure

what gauge do we use in anesthesia

bourdon gauges to measure high pressures, gas cylinders, and are referneced at atmospheric pressure

3 laws of thermodynamics


1 law of conservation of energy


2 energy moves toward greater entropy or randomness


3 absolute zero is void of all energy

1. energy cannot be created or destroyed


2 the entropy of an isolated system not in equilibrium will tend to increase over time


3. absolute zero is theoretical because it has been impossible to acheive

energy can be defined as the exertion of _____ or the capacity to do _______

force kinetic


work

Si unit for energy =

Joule

2 types of energy are

potential stored energy


kinetic movement

PE = formula

PE = mgh

KE = formula

KE = (1/2)mv^2

temp conversion




c to K


C to F


F to C

K= C +273


F = (1.8xC) + 32


C= (F -32)/1.8




SI unit of temp K


273.15K

absolute 0K, -273.15C, -459.67F means what

absolute zero is the absence of all energy and therefore absence of all heat

normal mechanism that slow heat loss in our body

vasoconstriction the directing of blood away from the periphery aids in conservation of body heat

opposite thermoregulation that promotes heat loss

vasodilation

thermoregulation under anesthesia

it is disrupted under anesthesia by vasodilating drugs, (gases) and regional, vasodilate vessels including those in the periphery causing greater blood flow to the surface of our bodies

the greatest heat loss is when

first hour

4 ways of heat loss


1 radiation


2 convection


3 conduction


4 evaporation




most significant heat loss

radiation*- of the infrared electromagnetic wavelength transfers heat energy from our warm bodies to the less warm OR


convection - is the process of creating air currents by heat CURRENTS


conduction - transfer of heat by physically touching a less warm object


evaporation - least important - moisture evaporated from skin and exhaling

where do we loose the most heat: body part

head d/t most blood flow to that area

latent heat of vaporization

is the amount of heat energy per unit mass required to convert a liquid into the vapor phase

the energy withdrawn from the environment to convert one gram of water into vapor is _____ joules or approx ____calories

2500


600

give an example in the OR of this

prepping the patient with betadine. the energy used to change the water to vapor comes from our body. our body loses heat energy to this process and we experience a state of lower thermal energy

of the 4 ways of hat loss which one is the most

due to radiation of infrared electromagnetic radiation then convection think CURRENT

give examples on how to prevent heat loss 5

forced warm air devices


lower gas flow rates


humidification


warm OR


covering and insulating patients

_________ is the process of converting liquid or solids into vapors

vaporization

The _____ _____ of ______ is the energy needed to transform a given amount of liquid into gas and is measured in _______

latent heat of vaporization


KJ

the temperature at which the bulk of a liquid at a given pressure converts to a vapor is the ___ ____

boiling point

the rate of vaporization depends on 3 things

temp


the vapor pressure of the liquid


partial pressure of the vapor above the evaporating liquid

all liquids that have high vapor pressures at room temp are known as _____ ______

volatile liquids

as gas molecules escape the liquid they exert a pressure known as ______ ______ measured in _____

vapor pressure


mm Hg

VP of


iso


sevo


des

238 mmhg


160


660

if a high vapor pressure volatile anesthetic agent is placed inside a vaporizer calibrated for a lower vapor pressure agent is the output higher or lower

higher than indicated on the control dial

The kinetic molecular theory states 5 assumptions

1. molecules have no volume


2 gas molecules exert no force on each other unless they collide


3. collisions do not decrease the energy of the system


4. molecule of gas are in constant motion


5. their energy is entirely kinetic energy

gas laws involve what 3 people and what 3 constants

charles


boyle


gay-lussac


pressure


temperature


volume



ideal gas law

PV=nrT

r=

0.0821 L atm/mol K

charles law

increase in temp increase volume

boyle law

increase in pressure decrease in volume

gay-lussac law

increase in pressure increase in temperature

avagadro's number

6.023x10^23 molecule

van der Waals equation corrects for the ideal gas law for 2 things:

molecular volume and molecular inter