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63 Cards in this Set
- Front
- Back
Where do most NT occur in children?
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PF
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Where do most NT occur in adults?
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Supratentorial (hemishperic)
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Name 3 cells that would test GFAP +
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Astrocyte (MAJOR ONE) Oligodendrocyte and Ependymal
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Which glioma is the most poorly defined?
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astrocytoma
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Which glioma is most circumscribed?
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Oligodendroglioma
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What NT ALWAYS extends beyond apparent margins and causes asymmetry?
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Astrocytoma
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Why do NT cause vasogenic edema?
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Neovascularization
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What has eosinophilic cell bodies with abundant, stout processes?
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Gemistocytic Astrocytoma
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What NT exhibits serpentine necrosis and pallasading>
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Glioblastoma Multiforme (GBM)
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What NT is there an > in VEGF and what does this form?
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GBM, forming glomeruloid bodies
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What can a brain stem glioma progress into?
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GBM
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Grade of pilocytic astrocytoma?
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1
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Where is the primary location of a pilocytic astrocytoma?
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Cerebellum
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Which NT is often cystic with mural nodules?
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Pilocytic Astrocytoma
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Which NT behaves like a hamartoma?
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Pilocytic Astrocytoma
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What do Rosenthal fibers contain?
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GFAP
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Grad of Oligodendroglioma?
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2 or 3
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Which NT will have microscopic hemorrhages?
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Oligodendroglioma
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Why is an oligodndroglioma associated with prolonged survival?
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Codeletion of 1p and 19q
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What NT will show halos?
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Oligo
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Which NT will show a delicate network of capillaries?
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Oligo
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Grade of Ependymoma?
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2 or 3
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Where is it most common to get an ependymoma?
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SC
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What secondary tumor is common to get with NF2?
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Ependymoma in SC
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What NTs would you see asymmetric non-comm hydrocephalus?
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Ependymoma and Medulloblastoma due to blocked foramen of monroe
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What age group is an ependymoma common in?
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children and adolescence
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BV surrounded by empendymal cells
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Pseudorosettes
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Adult varient of ependymoma
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Myxopapillary (filum terminale)
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What age group predominates in a medulloblastoma?
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children
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Where would you find a medulloblastoma usually?
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cerebellum (pilocytic too)
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What is the MOST likely NT to seed into CSF?
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Medulloblastoma (MORE than ependymoma)
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What NT shows drop metastisis?
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Medulloblastoma
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Where will you see true, Homer-Wright rosettes?
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Medulloblastoma
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Which NT may be of mixed origin?
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Medulloblastoma
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What is the chormosome abnormality of a medulloblastoma?
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i(17q)
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What is the most common tumor in immunosuppressed patients?
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Primary CNS lymphoma (EBV)
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What tumor would show large cells around BVs?
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Primary CNS lymphoma
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What NT would display Periventricular or Virchow Robin Spaces?
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Primary CNS Lymphoma
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Most common tumor to met to the brain?
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Lung
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Least common tumor to met to the brain?
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Prostate
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Why would you see SAS hemorrhage in CNS Leukemia?
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< Platelet = bleeding
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Where would you see transient sludging?
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CNS leukemia
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Where would you see penetration along V-R spaces?
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Luekemia and Lymphoma
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What tumor has progesterone receptors?
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Meningioma
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If mutltiple meningiomas, with acoustic neuromas/gliomas...think what?
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NF2
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What NT may be bosselated/polypoid?
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Meningioma
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Tumor spreads in a sheet-like fashion along the suface of the dura
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En Plaque
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Which NT would display syncytial whorled clusters?
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Meningioma
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What NT would display Psammomatous bodies from Ca or syncytial nests?
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Meningioma
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Where do most mets occur?
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Grey-white junction of cortex
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Plexifrom, or masses of tangled nerves are associated with what?
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NF1 (Enlargement of limbs)
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17q11.2
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NF1
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22q12
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NF2
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>or= 6 cafe au lauit spots
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NF1
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Lisch nodules (pigmented hamartomas)
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NF1 -DISTINGUISHING FACTOR
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Schwannomas including bilateral acoustic neuromas
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NF2
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What NT is very poorly defined?
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Astrocytoma
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Which NT are sharply circumscribed?
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Oligo, Mets, Medduloblastoma
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Which NT has Rosenthal Fibers
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Pilocytic Astrocytoma
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What NTs show En plaque
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Oligo, Meninioma, Mets
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What NTs show Ca?
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Oligo, Meningioma (Psamm)
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What NTs show NC hydroceph?
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Epend and Medulloblastoma
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What NT shows Rosettes?
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Ependymoma
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