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5 Cards in this Set

  • Front
  • Back
NITROPASTE
Class/ MOA
Class: Vasodilator
Mechanism of Action: Smooth muscle relaxant acting on vascular, bronchial, uterine and
intestinal smooth muscle. Dilation of arterioles and veins in the periphery reduces preload
and afterload, decreases the work load of the heart and, thereby, myocardial oxygen
demand.
NITROPASTE
I/ CI
Indications: Angina pectoris and chest pain associated with acute MI, CHF/PE; Hypertension
(HTN).
Contraindications: Hypotension, hypovolemia, Intracranial bleeding or head injury.
NITROPASTE
AR/ how supplied
Adverse Reactions: Headache, hypotension, syncope, reflex tachycardia, flushing.
Nausea, vomiting, diaphoresis, muscle twitching.
How Supplied: Topical Ointment: (Nitrolâ) 2% [20 mg/g] (30g, 60g)
NITROPASTE
Dose admin
Dosage and Administration
Adult: For CHF/PE; HTN
Paste: Apply 1 inch, cover with plastic wrap and secure with tape.
Pediatric: not recommended
NITROPASTE
Durration/ Special considerations
Duration of Action
Onset: 30 minutes.
Peak effect: Variable.
Duration: 18-24 hours.
Special Considerations
Pregnancy safety: Category C.
Apply in thin uniform layer on non-hairy area.
1 inch equals approximately 15 mg nitroglycerin.
Avoid using fingers to spread paste.
Store past in cool place with tube tightly capped.
Erratic absorption rates quite common.