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5 Cards in this Set
- Front
- Back
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a drug's distribution depends on what 3 factors?
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organ perfusion, protein binding, and lipid solubility
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in relation to distribution, name the 4 tissue groups and the % of CO they receive?
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Vessel rich- 75%
Muscle-19% Fat- 6% Vessel poor- 0% |
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if a drug is bound to plasma proteins, is it available for uptake?
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NO. This is why if the patient has a low albumin level, there will be more free drug available
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the redistribuition from the brain to less perfused areas like muscle or fat is responsible for the ________ of effect of some anesthetic drugs
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termination
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a small Vd means that the drug will stay mostly confined to the intravascular space. This will lead to a high or low plasma concentration?
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High. So low VD leads to High plasma concentrations
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