Pharm Test 3 Anticoagulants And Thrombolytics Ch.37

formation of a blood clot

the blot clot

thrombus that detaches from a blood vessels wall and travels through the blood stream

complex process by which fibrin forms and blood clots

When a blood vessel is injured, a series of events occurs to form a clot and stop the bleeding; this process is called _______

It involves a complex process called the ____ ___

When the thrombus detaches itself from the wall of the vessel and is carried along through the bloodstream, it becomes an _____

IF the embolus goes to the lung and obstructs a pulmonary vessel, it is called ____ ___

____ drugs prevent the formation of clots

drugs that suppress platelet aggregation

drugs that help to eliminate the clot

Anticoagulants have no ___ effect on an existing thrombus and do not reverse any damage from the thrombus

The drug taken orally for anticoagulation is

The drugs used parenterally are

peak activity for warfarin is __-__ days after therapy is initiated

Anticoagulants prevent the formations of extension of a ___, maintain potency of intravenous catheters, ____ for cardiovascular conditions

The common adverse reactions for anticoagulants are mild to severe ___, bruising, and petechiae. Aslo rash and ____

What are come drugs you would not want to give with an anticoagulant that would increase the risk for bleed?

an overdose of coumadin can cause hemorrhage, headache, ____ and back pain

uses for coumadin are

_____ interferes with vitamin K dependent clotting factors and reduces prothrombin

WHen on Warfarin take __ and __ daily until stable and then every 4-6 weeks

____ interferes with warfarin (coumadin)

high dietary amounts of vitamin K ___ effect and increase clot formation

Too much warfarin, ETOH, ASA can ___ effects and increase the risk of bleeding

These foods have a High potential to interact with these foods/herbs and increase the risk for bleeding:

Heparin solutions inhibit the formation of ___ clots, inhibit conversion of ___ to fibrin, and inactivate clotting factor ___ and thrombin

What are the heparins?

Heparin solutions are given in ____

The routes for heparins are

___ and ____ are taken daily to adjust the dose as needed

Heparin does not lyse or _____ up clots, it just delays their formation

When giving heparin SQ angle the needle at __-__ angle and the needle size is __-___ gauge 3/8" to 1"

The site used to administer heparin is the _____, upper arm, and upper thigh

No aspiration once needle is _____

No rubbing at the ___ after injection

When monitoring PTT/aPTT for heparin therapy, the therapeutic range is __-___ times the normal

PT and INR while monitoring Coumadin therapy has a therapeautic range __-___ times the control value

If PT is greater than 2.5 times the control value, or INR is greater than 4, the person will have ___ tendencies

When reading the labs, the higher the number the slower the ___

A nurse should monitor PT/INR until stable and with prescribed therapeutic range. ONgoing lab evaluations are every _-__ weeks

You will withhold the drug is PT is greater than __-___ times the control value or INR is over 3 or if there is evidence of bleeding

With heparin, ____ the dose according to daily aPTT monitoring

___ is used for warfarin overdose

Anitplatelet drugs ___ platelet aggregation

some examples of antiplatelet drugs:

These are given

adverse reactions of antiplatelet drugs

These drugs work by ____ the platelets ability to stick together in the blood, thus forming a clot

_____ drugs dissolves (lysis) all existing blood clots inside vessels

examples of thrombolytics are

Thrombolytics are administered