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46 Cards in this Set
- Front
- Back
Diuretics
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Potassium sparing, Loop, Thiazide
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where does spironolactone and eplerenon work?
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distal tubule and collecting duct
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bendroflumethiazide and cyclopenthiazide are
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thiazide drugs
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thiazide drug site of action
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distal tubule
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furosemide, bumetanide and torasemide are
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loop diuretics
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anti-diurectics
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vasopressin
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RAAS
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Renin-angiotensin-aldosterone system
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Anticoagulant drugs (rin)
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interfere with the clotting cascade
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what anticoagulant antagonises vitamin k?
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Warfarin
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what anticoagulant activates anti thrombin?
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Heparin
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Fibrinolytic
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dissolves pre existing clots
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what converts inactive plasminogen into active plasmin? (ase)
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Alteplase, streptokinase
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anti-fibrinolytic
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used with risk of bleeding
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what acid reduces activation of plasmin?
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Tranexamic acid
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Anti-hypertensive drugs A,B,C,D
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Ace inhibitors, beta blockers, calcium blockers, diuretics
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ACE inhibitor (pril)
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stops Angiotensin I converting to Angiotensin II
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what do Captopril, enalapril, ramipril do?
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Vasodilators
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where is the site of action for beta blockers?
What do they block? |
beta 1 receptors on SA node
adrenaline / noradrenaline |
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atenalol, bisoprolol, propanolol
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beta blockers
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what are nifedipine, amlodipine, nicardipine?
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calcium blockers
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what do calcium blockers interact with?
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grapefruit juice
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specific receptors
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lock and key mechanism
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membrane receptor drugs
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salbutamol
beta blockers anti histamines |
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local anaesthetics and benzodiazepine both bind it what kind of receptor?
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ion channels
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enzymes
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speed up reactions
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aspirin and viagra bind to what kind of receptor?
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Enzymes
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steroid based drugs bind to what kind of receptor?
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nuclear receptors
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Omeprazole and cocaine bind to what kind of receptor?
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carrier molecules/pumps
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what can treat hyperthyroidism?
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carbimazole - disrupts t3/t4 production
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what does levothyroxine do for hypothyroidism?
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T4 substitute as there's not enough iodine
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parathyroid hormone promotes...
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Ca2+ re absorption from the kidneys
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calcitonin
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inhibits ca2+ re absorption and decreases levels
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calcitriol
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increases levels by increasing re absorption from the gut
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what are salbutamol and salmetarol?
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beta 2 agonist
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what is theophylline and ipatropium site of action?
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Musculerinic agonist
blocks M receptors |
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what are atracurium and pamcuronium?
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Ach antagonists
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saxamethonium acts as a .... sustaining depolarisation of the muscle
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Ach agonist
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what channel does local anesthetics block?
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Na+
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anxiolytics and hypnotics increase...
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GABA
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where do stomach ulcer drugs lansoprazole, esomeprazole and pantoprazole bind to
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proton pump inhibitors
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stomach ulcer drugs cimetidine, famotidine, nizatidine and rantidine are all
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H2 receptor antagonists
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class 1 local anesthetic drugs block...
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Na+ channels
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Class II beta blockers bind to
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beta 1 adrenoceptor antagonists
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class III amidarone and sotalol interact with
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K+ channels
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class IV Verprimil slow down Av and SA node conduction by blocking
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Ca2+ channels
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Unclassified Digoxin increases O2 consumption and cardiac output by inhibiting the
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N+ / K+ pump
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