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26 Cards in this Set
- Front
- Back
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which organs would most likely show steatosis (fatty change)
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liver, heart, and lymph nodes
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what term refers to the deposition of choldesterol in the dermis, frequently tendons
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xanthoma
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upon microscopic examination of the liver it is possible to view the remnants of lipid droplets that are now called...
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vacuoles
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which two stains will stain fat
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oil red O positive and Sudan Black positive
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the accumulation of which specific lipid will cause atherosclerosis, xanthomas, foamy macrophages secondary to inflammation and necrosis, and cholesterolosis of the gallbladder
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cholesterol
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in an atherosclerotic vessel, small needle shaped opening are observed which are called
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cholesterol clefts
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foamy macrophages/histiocytes are filled with
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cholesterol and cholesterol esters
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eosinophilic inclusions found in the liver as a result of protein accumulation are called
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Russell Bodies
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what stain will help to identify amyloidosis by use of a polarizer to observe an apple green color
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Congo Red Stain
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what stain can be used to identify glycogen deposits
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Periodic Acid Schiff Stain with or without Diastase
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Which pigments are considered to be the wear and tear pigments, and is indicative of free radical injury and lipid peroxidation
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lipofuscin pigments
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what stain can be used to identify lipofuscin pigments
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Periodic Acid Schiff Stain
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skin lesions will have what pigment in them, which may represent a benign to very malignant tumor
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melanin
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what stain is used to identify melanin
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fontana stain or fontana-masson stain
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what pigment represents old hemorrhage, excess accumulation of iron, or hemolysis
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Iron/Hemosiderin
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what stain is used to identify Iron/hemosiderin
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Prussian blue stain
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what stain is used to identify bilirubin
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prussian blue negative
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what are laminated calficiations called that look like a jaw breaker
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psammoma bodies
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what type of calcification occurs locally in dead or dying cells and is common in atherosclerosis
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dytropthic calcification
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what type of calcification occurs everywhere and is a result of profound or sustained hypercalcemia
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metastatic calcification
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what term refers to any form of glassy, eosinophilic, relatively acellular change in H&E sections
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hyaline change
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after a certain number of divisions a cell stops dividing and is called a...
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senescent cell (may involve clock genes)
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what is the most important thing that is thought to cause cellular aging
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Free Radicals
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neurodegenerative diseases such as Alzheimer's, Huntington's, Parkinson's, cystic fibrosis and amyloidosis is due to...
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protein folding defects
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what term is defined as toxic accumulations of abnormally folded proteins
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amyloidosis
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pigments come in two types: exogenous and endogenous. What are two classic examples of exogenous pigments
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carbon/coal and tattooing
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