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32 Cards in this Set

  • Front
  • Back

Fibrinolytic

alteplase

Side effects of heparin

bleeding


thrombocytopenia


osteoporosis


skin necrosis


hypersensitivity reaction


hyperkalemia


hypoaldosteronism

Monitoring of heparin

aPTT


Factor Xa

Antidote of heparin

protamone sulfate

Low molecular weight heparin(enoxaparin, lovenox)

longer half life


more predictable


lower bleeding risks

Aspirin

recommended 24-48 hours post stroke


If tPA, hold 24 hrs


325mg po or rectal


-persist in system for 7-10days


-don't take with NSAIDs

Aspirin and dypiridamole

aggrenox


Most common side dffect headache due to vasodilation

Warfarin

Vitamin k antagonist


stays in the system 2-5 days


Monitor PT/INR (2.5-4.2)

Complications of warfarin

warfarin necrosis


osteoporosis


purple toe syndrome(3-8wks treatment)

Dibigatran(Pradaxa)

direct thrombin inhibitor


no monitoring


no antidote

Rivaroxaban(Xarelto)

half life: 5-9hours


cleared renal ,hepatic and fecal

Apixaban(Eliquis)

half life: 8-15hrs


direct Xa inhibitor

Statins

decrease total cholesterol


stabilizes plaque


anti inflammatory effects


Don't take with grapefruit juice

Adverse side effect of clevidipine

AF


Pancreatitis


Allergic reaction to eggs and soy

Nitroprusside

direct vasodilator


coronary artery steal( steals oxygen from ischemic areas to non ischemic are


Methemoglobina- can't carry oxygen

Dopamine

alpha stimulant

Mannitol

os.otic diuretic


monitor serum and sodium osmolality

Lacosamide

Sodium channel blocker


side effect-diplopia and renal stones

Only drug approved for primary prevention

aspirin

reversal of warfarin

vitamin K


FFP


Rivarxaban(xarelto)

only direct thrombin inhibitor you can crushed

tPA

within 10mins of completion,


80percent of drug is out of the system

Goal INR with warfarin

2.5-4.2

Adverse reaction of tPA

Angioedema


Anaphylaxis


ICH



adverse reaction of hydralazine

reflex tachycardia

Glycemic control recommendation

140-180

Baclofen withdrawal syndrome

fever


rash


seizure


cardiac instability

Antispasmodics

Tizanidine


baclofen


dantrolene


botox

antidepressant

may take 4-6 weeks to feel full effect

neurostimulants

used post stroke to accelerate and improve motor recovery or cognitive recovery

nicardipine


titrable


2.5mg every 15minutes

adverse reaction of valproic

increased ammonia