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90 Cards in this Set

  • Front
  • Back

skin is what % of a dog's body weight?

12%
epidermis is derived from what embryonic tissue type?
ectoderm
the dermis is derived from what embryonic tissue type?
mesenchymal
what are the 3 major layers of the epidermis
stratum cylindricum

stratum spinosum

stratum corneum
the stratum cylindricum and stratum spinosum collectively are known as what?
stratum germinativum
what percent of dermal fibers in the dermis are composed of collagen?
90%
the 2 indistinct layers of the dermis are the:
superficial stratum papillare
deep stratum reticulare

the stratum papillare has what type of fibers?

the stratum reticulare has what type of fibers?

papillare: fine elastic and reticular fibers

reticulare: dense collagen bundles
what does the adnexa of skin include?
hair follicles
sweat glands
sebaceous glands

all are of ectodermal origin
Errector pilli muscles are innervated by?
autonomic nervous system
hair follicle pigmentation granules come in what 3 colors?
brown, black, yellow
Anal sac is lined with what cell type?s
stratified squamous epithelium
define apocrine
the secreted product is concentrated at the free end and is release with a small amount of cytoplasm
define holocrine
the entire secreting cell is release as part of the secreted product
define neurocrine
the secreting cell remains intact through the dormation and secretion of the product
the panniculus musculature is composed of which muscles?

platysma

sphincter colli superficialis

sphincter colle profundus

cutaneous trunci

in the cat, the platysma is subdivided in the cervical region into what 2 muscles, and along what line?
supercervicocutaneous muscle and
cervicofacial muscle

divided along the line of attachment to the skin
what are the 3 levels of the cutaneous vascular system?
the deep, subdermal, or subcutaneous plexus

the middle, or cutaneous plexus

the superficial or subpapillary plexus
which of the 3 plexuses is the major vascular network to the underlying skin?
the deep, subdermal, or papillary plexus
why does canine skin generally not blister with superficial burns?
because their capillary loop system andpapillary bdies of their vascular system are poorly developed
where should skin be undermined to avoid cutting off its vital blood supply?
In the fascial plane beneath the cutaneous musculature to preserve the subdermal plexus

HOWEVER, if the area is devoid of musculature, one should undermine in the fascial plane well below the dermal surface
tissue expanders, presuturing, and skin stretchers all take advantage of what phenomenon
mechanical creep
clinical features of cutaneous asthenia are
increased skin fragility
hyperelasticity
laxity
2 layers of skin? and beneath that
epidermis
dermis

and hypodermis beneath composed of fat and CT
differences in skin blood supply between dogs and cats
dogs: greater density of collateral sq vessels

cats: smaller number and wider distribution of cutaneous perforators
another term for primary wound healing
first intention healing
healing of sutured wound (def)
2 other terms for delayed primary closure?

definition?

secondary closure

third intention healing
closure performed 5 or more days after wound initiation

second intention healing
heals without suturing
how do healing rates doffer between primary and secondary healing?
same, except with primary the area is smaller

rate of epithilialization?

is tissue as strong as skin

1mm/day

no
tensile strength of a 5mm wide strip normal canine skin?
9.9kg

how strong is wounded skin in comparison to normal skin?
2 weeks post op?
3-4 weeks?
several months
one year

5-10% as strong at 14d post sx

25% as strong at 3-4 weeks

70-80% at several months

80% at 1 year
strength of sutured wounds in cats compared to dogs?

one stuy wounds were only half as strong as in dogs at 7d post op

what is false healing?

in cats, where wounds appear healed and then dehisce after suture removal

cats vs dogs, vascularity and wound strength

cats lowere perfusion first week post op followed by more rapid gain during second week.



by 2 weeks perfusion was the same



lower wound breaking strength than dogs at 7d post op



cats have more problems with healing. may ant to leave sutures in longer than 2 weeks

effect of SQ removal on wound healing?
in one study all tissues deep to panniculus but superficial to thoracodorsal muscle fascia was removed, no effect on skin healing.
A. Epidermis
B. Dermis
C. Hypodermis
D. Cutaneous Trunci
describe differences between canine and human blood supply

describe differences between canine and human blood supply

major cutaneous vessels in dogs are parallel to skin whereas in humans they are perpendicular

healing of primary wounds influenced by what factors?

tension
pressure
motion
self-mutilation
patient health

skin wounds usually closed parallel to lines of tension except where

in limbs they may need to be closed perpendicular
patient factors that significantly effect wound healing include:
uremia
steroid admin
hyperadrenocorticism
geriatric status
malnutrition
how does geriatric status affect wound healing?
decreased cutaneous perfusion
increased skin fragility
increased risk of infection
how does malnutrition effect wound healing?

decreased albumin and hemoglobin levels

rat study: starved one group of rats for 2 weeks. measured wound strength and hydroxyproline in normal and malnourished rats

malnurished groups reached same wound strength and hydroxyproline levels at 60d as normal rats at 21d

what did they find in a study comparing monocryl with vicryl for intradermal sutures
vicryl group had more early swelling and redness, but there was no difference between the two groups later
name 2 important amino acids for wound healing
cysteine
methionone

also, glutamine, arginine, zinc, fatty acids
vitamin E
name 2 advantages of eltrocautery for incisions
hemostasis
lymphatic sealing
what is knot security of surgeons vs square

how many throws are necessary for different suture types for secure knot at START of continuous line?
surgeons and square had same security

polyglycolic acid: 3
polyglactin 910: 3
polypropylene: 3

chromic gut: 4

PDS: 5
nylon: 5
whic considered better for small animal incisions: cautery or sharp and why?

wound strength between the two?
sharp

cautery (if used improperly)can cause thermal damage to wound that affects cutaneous perfusion and delays healing

sharp incisions had twice the wound strength as those made with cautery at 7-10d post op

scalpel incision had less drainage and faster/stronger healing
when skin is incised by radiowaves, CO2 laser, monopolar electrocautery, how far will char extend?
radiowaves: 0.171mm
Co2: 0.215
monopolar:0.255
one way of hemostasis with small vessels

if less than 1mm, ,can grasp with hemostats and twist 360 degrees multiple times.= to a ligature in small vessels

when is the "golden period"?
up to 3-6 hours after wound initiation. within this time bacteria can mutliple to 10^5 per gram of tissue or mm of exudate
how long does it take for degree of tissue necrosis to be established in crushing wounds?
3-7days
describe steps
how many throws are necessary for different suture types for secure knot at END of continuous line?
polyglycolic acid: 5
polypropylene: 5
chromic gut: 5

polyglactin 910: 6
nylon: 6

PDS:7
aberdeen compared to square
equally secure
does tight SQ closure compromise skin vascular supply
not proven
study looking at SQ vs no SQ layer closure in cats?
no difference grossly, microscopically less seroma in those with SQ layer closed
what was foudn in dog study looking at monocryl for intradermal closure vs monocryl or prolene skin sutures?
intradermal group had more initial post op swelling and redness but fewer complciations overal by 10-14d

use of absorbably monocryl for skin sutures was associated with more incisional swelling and discharge at 14d post op
what did they find in study looking at wound birsting strength with sutures placed 3, 6, or 10mm from linea alba in rats?
immediately: sutures placed 10mm away had higher bursting strength

at 4d sutures placed 3 or 6mm (and at closer intervals) had higher bursting strength
study looking at spays closed with intradermal monocryl vs cutaneous sutures found what?
more inflammtion 18-24 hours post in intradermal group, less inflammation at 10-14d

also, intradermal assctd with less pain in women
what is the tucking maneuver?
smurfing
tissue adhesives vs. skin sutures?

one study which created random pattern skin flaps in dogs found that wounds closed with skin sutures vs glue and few skin sutures had equal tensile strength

but one day post op glue had less tensile stength (only 15% of sutured group), so not recommended for wounds under tension

glue can cause foreign body reaction in SQ

fibrin sealants
human and bovine have been studied.
do not increase wound breaking strength over sutures alone

only used experimentally
how long does it take dog ears to regress in human studies?

ears less than 8mm regress completely by 132 days

how do lidocaine and bupivicaine work?

bind to neuronal membrane receptors, inhibiting Na ion influx. membranes become less stable, which inhibits initiation of action potential and conduction of nerve impulses, preventing pain sensation

what is a step defect and what is the consequence

name 3 ways to correct this

what is a step defect and what is the consequence

name 3 ways to correct this

when wound edges are not opposed in level fashion

epithelialiazation is delayed

1.bites at same depth on either side of incision
2.half buried horizontal mattress sutures
3.stiff suture across wound to elevate low side

when wound edges are not opposed in level fashion

epithelialiazation is delayed

1.bites at same depth on either side of incision
2.half buried horizontal mattress sutures
3.stiff suture across wound to elevate low side



image on front of slide is demonstrating dog ear, with apex cutaneous suture used to correct it

triple ab over primarily closed wounds
provide moisture
may enhance epithelialization
do NSAIDS effect wound healing?

theoretically should but studies have shown no effect

dogs, rats, mice
rats: no effect on tile strength at 3-7d
mice: no effect on healing at 28d

what happens with application of 5% lidocaine patches to wounds in humans
blocks pain, but can still feel pressure, touch, temperature
pharmacokinetics of 5% lidocaine patches applied to normal skin in dogs?

systemic absorption by 12 hours,
steady state by 24-48 hours post applilcation
dramatic decline in drug [ ] after 60 hours

low blood levels until 6 hours post patch removal

has not been reported for when applied over wound

local block before or after skin incision?

affect on wound healing?
before. one study showed that when blocked before skin incision was made dogs had lower post-op pain scores and required less opiod that when blocked after skin incision

analgesic effect seemed to last for 24hours (longer than expected based on halflife)

no deleterious effects on wound healing in this study

how deep do cold packs penetrate?how long should they be left on and why?

all the way to periosteum

not longer than 20min to avoid injury or delayed wound healing from vasoconstriction

wounds that are perfectly apposed can have an epithelial seal within ___ hours?

24

under what circumstances would you consider closing a traumatic wound primarily?

if occurred within 3-6 hours,


wound edges fresh and vascularized


no evidence or history of crushing injury


no visible contamination or debris after wound contamination


what do they call the loop at the end of the suture line?

penultimate loop

how long should suture tags be?

3-4mm for buried knots

what needle type is recommended for sq closure?

1/2 or 3/8 circle taper

does a continuous SQ layer compromis blood supply more than an interrupted layer?

some think so, but no evidence

where should tacking sutures be avoided?

in areas where skin moves freely(over thorax)

how big should bites in SQ be?

0.5-1cm

how are intradermal and subcuticular different?

they are the same

what are the 2 different types of intradermal closure?

vertical: bites placed perpindicular to skin edge, incorporate sq



horizontal, along skin edge, just dermis

needle type for skin sutures?

usually 3/8 circle on cutting

does horizontal mattress sutures result in inverting/everting/apposition?

any, depending on how they are placed

does vertical mattress result in apposition, inverting or everting

everting or apposition

what is a benefit to ford interlocking?

same fetures as continuous, but if line breaks, the locking may keep incision opposed partly

which is stronger in tissues under tension, horizontal or vertical mattress?

vertical

how are bites taken for a vertical mattress intradermal pattern?

from deep to superficial on near side, and from superficial to deep on far side



benefit is that you are unlikely to compromised blood supply-because suture is parallel to cutaneous perforator vessels

describe these ways to correct a dog a dog ear

A:removal of  small triangles


B: removal of one large triangle


C: removal of ellipse


D: removl of arrowhead


E. half z correction

A:removal of small triangles


B: removal of one large triangle


C: removal of ellipse


D: removl of arrowhead


E. half z correction

what are some ways to correct crescent shaped defects?