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8 Cards in this Set
- Front
- Back
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........... is the most prevalent form of arthritis in West Africa. |
Osteoarthritis is the most prevalent form of arthritis in West Africa. |
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Symptoms occur earlier and appear to be more severe in ? |
Symptoms occur earlier and appear to be more severe in women. |
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Epidemiology of Osteoarthritis Drop 2 points |
1. Osteoarthritis is the most prevalent form of arthritis in West Africa. 2. Symptoms occur earlier and appear to be more severe in women. |
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Osteoarthritis is A degenerative, non-inflammatory joint disease characterized by |
1. destruction of articular cartilage and 2. formation of new bone at joint surfaces and margins. |
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Define Osteoarthritis |
A degenerative, non-inflammatory joint disease characterized by destruction of articular cartilage and formation of new bone at joint surfaces and margins” |
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Osteoarthritis is purely a degenerative disorder. True or false |
False. It is not a pure degenerative disorder but a dynamic phenomenon since it shows features of both destruction and repair |
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With Age, cartilage shows, |
1. Diminished cellularity, 2. Reduced proteoglycans concentration, 3. loss of elasticity and 4. a decrease in breaking strength . |
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List the aetiology of osteoarthritis |
1. Age; with age cartilage shows a. diminished cellularity, b. reduced proteoglycans concentration, c. loss of elasticity and d. a decrease in breaking strength .
2. Cartilage problems: a. crystal deposition diseases,
3. Genetic defects in type 11 collagen 4. Previous inflammatory disorders 5. Destruction and reduced synthesis of proteoglycan: e.g. a. synovial and leucocytes enzymes causing leaching, while
6. Deformities, joint incongruity and instability: increases mechanical stress due to abnormal loading in knee deformities and acetabular 7. Changes in subchondral bone: malunited fractures 8. Joint dysplasias 9. Occupation: Those which cause repetitive stress eg a. knee bending activities b. Footballers and athletes 10. Bone density- (genetic, hormonal & metabolic factors) 11. Obesity 12. Family history |
