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21 Cards in this Set
- Front
- Back
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H. pylori virulence factor
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Vacuolating cytotoxin A vacA
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Beta virulence factor in s. aureus
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spingomyelinase
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Alpha hemolysin virulence factor in s. aureus
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Pore forming beta barrel toxin; allows cationic flux across membrane, producing DNA degradation and apoptosis
correlated w virulence in s. aureus pneumonia |
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Exfoliatin
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s. aureus exotoxin which causes staphylococcal scalded skin syndrome; the protease activity of the exofoliative toxin causes peeling of the skin obsersed with SSSS
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What virulence factor causes scalded skin syndrome?
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Exofoliatin via s. aureus
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Toxic Shock Syndrome Toxin
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Superantigen via s. aureus
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staphylococcal enterotixin B
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SEB; food poisoning, is a heat stable (ST) toxin
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Panton-Valentine leukocidin
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Associated w severe necrotizing pneumonia in children; Beta pore forming toxin and superantigen - PVL factor is encoded on prophage producing two proteins LukS-PV and LukF-PV
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Neonatal septis, meningitis
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Streptococcus agalactiae (group B hemolytic)
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Endocarditis
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Streptococcus viridians (GAS)
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Endocarditis in immunocompromised, pneumonia, meningitis
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Nocardia brasiliensis
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Motile, "swarming"
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Proteuse sp
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Gram negative diplococci, capsulated
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Neisseria meningitidis
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Catalase +, superoxide dimutase +, cord factor
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Nocardia asteroides
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Hemolytic Uremic Syndrome
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Infection in digestive system produces toxic substances which destroy RBC causes kidney injury; commonly due to E. coli
MCC acute kidney failure in children |
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Tennis racket or drum stick appearance
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Clostridium tetani
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Eye infection (trachoma) lymphogranuloma venerum, urehtritis, infertility
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Chlamydia trachomatis
Obligate intracellular pathogen |
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Abdominal sepsis, abscesses
Involved in 90% of peritonitis |
Bacteroides sp
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Oppotunistic pneumonia
Soldiers in Iraq, peritoneal dialysis, urinary catheters |
Acinetobacter baumanni
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Flagellated, causing meningitis and septicemia in immunocompromised neonates
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Listeria monocytogenes
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Respiratory tract (COPD, otitis media)
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Moraxella catarrhalis
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