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115 Cards in this Set
- Front
- Back
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Posthepatic venous thrombosis. Abdominal pain, ascites, hepatosplenomegaly. Same as CHF except no JVD.
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Budd Chiari Syndrome
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Achilles tendon xanthoma
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Familial hypercholesterolemia
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Meningococcemia, Adrenal Hemorrhage, hypotension, DIC.
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Waterhouse-Friderichsen Syndrome. Neisseria Meningitidis Sepsis.
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Arachnodactyly, lens dislocations, aortic dissection, hyperflexible joints.
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Marfan's Syndrome. Fibrillin Defect.
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Vertebral tuberculosis. Back Pain, fever, night sweats, weight loss.
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Pott's Disease
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Fever, night sweats, weight loss.
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TB and B symptoms of Hodgkins
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Babinski's sign
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UMN lesion. Big toe extension/fanning upon plantar scrape. Hyperreflexia.
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Sarcoidosis
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Noncaseating granulomatosis. Bilateral hilar adenopathy, uveitis.
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Osteogenesis Imperfecta
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Blue Sclera. Type 1 collagen defect.
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Burton's Line
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Lead poisoning. Bluish line on gingiva.
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Increased hat size, bone pain, bone enlargement, arthritis.
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Paget's disease of bone. Increased osteoblast and osteoclast activity (bone turnover).
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Café au lait spots, lisch nodules (iris hamartoma).
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Neurofibromatosis type I
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Café au lait spots, lisch nodules (iris hamartoma), AND bilateral acoustic neuromas.
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Neurofibromatosis type II
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Calf pseudohypertrophy, Gower's sign (child uses hands to stand up from squat).
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Duchene's Muscular Dystrophy. X linked recessive Dystrophin defect.
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Cherry red spot on macula.
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Tay Sachs (ganglioside accumulation), Niemann-Pick (lysosomal storage disease, Central Retinal Artery Occlusion
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Autoimmune mediated post MI fibrinous pericarditis (weeks after MI). Chest pain, pericardial effusion/friction rub, persistent fever following MI.
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Dressler's Syndrome
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Child with fever develops red rash on face that spreads to body.
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"Slapped Cheeks" Parvovirus B19.
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Huntington's Disease
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Autosomal dominant trinucleotide (CAG) repeat expansion. 3 C's, Chorea, Crazy, Caudate degeneration, ACh deficiency.
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Chronic exercise intolerance with myalgia, fatigue, painful cramps.
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McArdle's Syndrome. Muscle Phosphorylase deficiency.
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Cold intolerance
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Hypothyroidism
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Patent Ductus Arteriosus
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Close with indomethacin, open with misoprostol. Continuous "machinery" heart murmur.
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Myxedema
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Grave's Disease (autoimmune hyperthyroidism) OR Hypothyroidism, cutaneous/dermal edema due to connective tissue deposition.
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Dark purple skin/mouth nodules.
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Kaposi's Sarcoma (Aid's patients, HHV-8, gay men)
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Kussmaul breathing
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Diabetic ketoacidosis. Deep, labored breathing/hyperventilation to blow off CO2.
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Pellagra
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Niacin (Vit B3) deficiency. 3 D's, Dermatitis, dementia, diarrhea.
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Wet Beriberi
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Thiamine (vit B1 deficiency). Dilated cardiomyopathy, edema, polyneuropathy.
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Pasteurella multocida
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Dog or cat bite with infection/cellulitis.
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Dry eyes, dry mouth, arthritis (autoimmune destruction of lacrimal and salivary glands)
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Sjogren's syndrome
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Dysphagia (esophageal webs), glossitis, iron deficiency anemia (may progress to esophageal squamous cell carcinoma)
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Plummer Vinson Syndrome
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Ehlers-Danlos Syndrome
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Elastic skin, hypermobility of joints, collagen type 3 defect
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Abdominal metastasis. Enlarged, hard left supraclavicular node.
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Virchow's Node
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Chvostek's Sign
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Hypocalcemia. Facial muscle spasm upon tapping. Ch for cheek and chvostek's sign.
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Gall stones, gall bladder, Fat, Female, Forty, and Fertile. 4 F's.
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Acute cholelithiasis (bile duct blockage)
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Jarisch-Herxhimer reaction
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Rapd lysis of spirochetes results in toxin release. Fever, chills, headache, myalgia following antibiotic trtmnt for syphilis.
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Fever and 3 C's. cough, conjuncitivitis, coryza, diffuse rash.
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Measles (Morbillivirus)
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B symptoms (lymphoma) OR TB
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Fever, night sweats, weight loss.
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Peyronie's Disease
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Connective tissue disorder, fibrous plaques in soft tissue of penis.
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Gout, Mental retardation, self-mutilating behavior in a boy.
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Lesch-Nyhan Syndrome. HGRPT Deficiency (enzyme of purine salvage).
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Green rings around periph cornea.
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Kayser-Fleischer Rings. Copper accumulation from Wilson's.
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Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands
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Peutz-Jeghers Syndrome. Genetic benign polyposis can cause bowel obstruction and increased cancer risk.
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Hepatosplenomegaly, osteoporosis, neurologic symptoms
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Gaucher's Disease. Glucocerebrosidase deficiency.
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Hereditary nephritis, sensorineural hearing loss, cataracts.
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Collagen mutation. Can't see, can't pee, can't hear. Alport's Syndrome.
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Hyperphagia, hypersexuality, hyperorality, hyperdocility.
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Kluver-Bucy syndrome. Bilateral amygdala lesion.
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Hypertensin, hypokalemia, metabolic acidosis.
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Conn's syndrome. Primary hyperaldosteronism.
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"Blue Bloater"
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Chronic bronchitis: hyperplasia of mucous cells. Hypoxemia, polycythemia, hypercapnia.
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Indurated, ulcerated genital lesion (non painful).
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Chancre. Primary Syphilis, Treponema Pallidum.
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Niemmann-Pick Disease
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Genetic Sphingomyelinase deficiency. Infant with failure to thrive, hepatosplenomegaly, neurodegeneration, cherry red spot on macula.
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Infant with hypoglycemia, failure to thrive, hepatomegaly. No glycogenolysis.
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Cori's Disease. Debranching enzyme deficiency.
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Infant with hypoglycemia, fialure to thrive, hepatomegaly. Absent gluconeogenesis, absent glycogenolysis.
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Von Gierl's Disease
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Infant with micrcephaly, rocker-bottom feet, structural heart defect
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Edward's Syndrome. Trisomy 18
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Jaundice, RUQ pain, fever.
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Charcot's triad (Ascending cholangitis)
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Keratin Pearls
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Squamous Cell Carcinoma
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Large rash with Bull's eye appearance.
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Erythema chronica migrans. Tick bite, borrelia, lyme disease.
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Male child, recurrent infections, no mature B cells. X-linked agammaglobulinemia.
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Bruton's disease. Boys, B Cells for Bruton's.
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Defect in platelet aggregation due to lack of GpIIb/IIIa. Mucosal bleeding and prolonged bleeding time.
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Glanzmann's Thrombasthenia
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Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumary teeth.
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Garder's Syndrome (genetic disorder). Predisposes to colon cancer
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Hemoptysis and glomerular disease. Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis.
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Wegener's and Goodpasture's syndromes. Wegener's also has sinus/palate problems.
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Waiter's tip. Neonate with arm paralysis and clavicle fracture after birth.
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Erb-Duchenne Palsy. Superior trunk (C5-6) brachial plexus injury.
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No lactation postpartum, absent menstruation, cold intolerance.
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Sheehan's syndrome. Pituitary infarction. Hemorrhage during birth leads to hypotension leads to pituitary infarction.
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Nystagmus, intention tremor, scanning speech
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Charcot's triad (MS)
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Oscillating slow/fast breathing.
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Cheyne-Stokes Resperiations. Caused by central apnea in CHF or increased ICP.
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Painful blue fingers/toes, hemolytic anemia.
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Cold Agglutinin Disease (IgM). Caused by autoimmune hemolutic anemia (Mycoplasma pneumoniae) or infectious mononucleosis (EBV)
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Painful, pale, cold fingers/toes.
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Raynaud's syndrome. Vasospasm in extremity.
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Painful, raised red lesions on palms and soles.
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Osler's node. Infective Endocarditis.
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Painless Jaundice
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Cancer of the pancreatic head obstructing bile duct
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IgA vasculitis affecting skin and kidneys. Palpable purpura, joint pain, abdominal pain (child), renal disease
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Henoch-Schlonlein purpura
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MEN 1 (Multiple Endocrine neoplasia). Pancreatic, pituitary, parathyroid tumors.
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Wermer's Syndrome
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Emphysema: centroacinar (smoking), panacinar (alpha1-antitrypsin deficiency). Pink complexion, dyspnea, hyperventilation.
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"Pink puffer"
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Mosaic G-protein signaling mutation. Polyostotic fibrous dysplasia, precocious puberty, café au lait spots, short stature in a young girl, multiple unilateral bone lesions.
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McCune-Albright syndrome
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Proximal tubular reabsorption defect, get rid of too much stuff. Polyuria, acidosis, growth failure, electrolyte imbalances.
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Fanconi's Syndrome
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Sympathetic chain lesion caused by Pancose tumor in apex of lung. Ptosis, miosis, anhidrosis (no sweat).
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Horner's Syndrome
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Neurosyphilis, pupil accomodates but doesn't react.
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Argyll Robertson Pupil (Prostitute's pupil)
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Autoimmune acute inflammatory demyelinating abnormality. Rapidly progessive leg weakness that ascends following GI/upper respiratory infection.
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Guillan Barre Syndrome
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Rash on Palms and Soles.
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Secondary Syphilis, RMSF, Coxsackie A virus (hand foot mouth)
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Neurtophil chemotaxis abnormality. Recurrent colds, unusual eczema, high IgE.
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Hyper IgE (Job's syndrome)
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Red "Currant Jelly" Sputum.
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Klebsiella pneumoniae
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Red, itchy, swollen rash of nipple/aereola
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Paget's Disease of Breast indictating underlying neoplasm
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Red urine in the morning.
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Paroxysmal noctural hemoglobinuria. Lack CD55 and CD59 so attack own RBCs.
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Renal cell carcinoma, hemangioblastomas, angiomatosis, pheochromocytomas.
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von-Hippel Lindau disease. Dominant tumor suppressor gene mutation.
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Resting tremor (pill roll tremor), rigidity, akinesia, postural instability
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Parkinson's disease. Nigrostriatal dopamine depletion.
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Restrictive Cardiomyopathy (juvenile cardiomegaly), exercise intolerance
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Pempe's Disease (lysosomal glucosidase deficiency)
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Retinal hemorrhages with pale centers
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Roth's Spots (bacterial endocarditis)
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Severe RLQ pain with rebound tenderness
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McBurney's Sign. Appendicitis.
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Short stature, increased incidence of tumors/leukemia, aplastic anemia
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Fanconi's anemia (genetically inherited can progress to AML)
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Single palm Crease
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Symian crease, Down Syndrome
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Severe Jaundice in neonate
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Crigler-Najjar Syndrome. Congenital unconjugated hyperbilirubinemia
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Situs inversus (organs reversed), chronic sinusitis, bronchiectasis, infertility
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Kartagener's syndrome. Dynein defect affecting cilia.
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Skin hyperpigmentation
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Addison's Disease. Primary adrenocortical insufficiency of autoimmune or infectious etiology.
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Slow progressive muscle weakness in boys
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Becker's Muscular Dystrophy. X-linked defective dystrophin, less severe than Duchenne's.
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Small, irregular red spots on buccal/lingual mucosa with blue-white centers
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Koplik Spots (Measles)
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Small, nontender, erythematous lesions on palms/soles
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Janeway Lesions (infective endocarditis)
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Smooth, flat moist white lesions on genitals
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Condylomata lata. Secondary syphilis.
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Splinter hemorrhages in fingernails
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Bacterial endocarditis
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Strawberry Tongue
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Scarlet Fever (GAS), Kawasaki's disease
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Smooth Glossy Tongue, Glossitis
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Vitamin B Deficiency
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Streak ovaries, horseshoe kidney, coarctation of the aorta
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Turner's Syndrome. XO (45 chromosomes), short stature, webbed neck, lymphedema.
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Sudden Swollen/big toe joint, tophi
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Gout/Podagra (hyperurecimia). Yellow and parrallel.
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Systolic ejection murmur (late), cresccendo-decrescendo
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Aortic Valve Stenosis
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Early systolic ejection murmor in mitral/tricuspid area
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Aortic Regurgitation
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Swollen gums, mucous bleeding, poor wound healing, spots on skin
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Scurvy. Vitamin C deficiency. Can't hydroxylate proline/lysine for collagen synthesis.
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Swollen hard painful finger joints.
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Osteoarthritis
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Osteophytes on PIP in osteoarthritis
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Brouchard's Nodes
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Osteophytes on DIP in osteoarthritis
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Heberden's Nodes
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Medulary Thyroid, parathyroid, adrenal tumors
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Sipple's Syndrome (MEN 2A) Pheochromocytoma.
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Ulcerated genital lesion with exudate (painful)
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Chancroid (Haemophilus ducreyi)
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Unilateral face drooping
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Bell's palsy (LMN CNVII Palsy).
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Upper and Lower drooping of face
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Bilateral Bell's palsy seen in Guillan Barre or Lyme Disease (Borrelia Burdorferi)
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Urethritis, conjunctivitis, arthritis in a male. Can't see can't pee can't climb a tree.
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Reiter's Syndrome (HLA-B27). PAIR= seronegative spondyloarthropathies. Psoriatic arthritis, ankylosing spondylitis, IBD, Reiter's syndrome.
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Vascular Birthmark (Port Wine stain)
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Hemangioma. Benign but associated with Sturge Weber Disease on opthalmic trigeminal distribution.
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Vasculitis from exposure to endotoxin causing glomerular thrombosis
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Shwartzman Reaction following second exposure to endotoxin.
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Vomiting blood following esophagogastric lacerations.
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Mallory-Weiss Syndrome. Alcoholics and eating disorders.
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Waxy castas with low urine flow
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End Stage Renal Disease
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WBC Casts in urine
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Acute Pyelonephritis
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Weight loss, diarrhea, arthritis, fever, adenopathy
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Whipple's disease (Tropheryma whippelii)
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What is associated with adult polycystic kidney disease
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Berry Aneurysm rupture to subarrachnoid hemmorhage.
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