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25 Cards in this Set
- Front
- Back
define virus
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self-rreplicating nucleoprotien
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What is a viron?
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mature (complete) virus particle
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This is the smallest amount of virus/volume capable of producing the reaction being measured.
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Infectious unit
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Which kind of virus induces cytolysis when exiting the cell?
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nonenveloped
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Which phase msut a cell be in to have the components available for DNA synthesis>
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s-phase
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This is the viral encoded protein coat surrounding the core.
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capsid
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This is the capsid and its enclosed core.
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nucleocapsid
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What are the three envelope proteins?
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peplomer
viral attatchment proteins antigenic proteins |
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This is a bridge between the nucleocapsid and the internal membrane of the envelope.
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matrix protein
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what are the four possible cytopathic effects of virus?
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cell lysis
syncytia formation inclusion bodies transformation |
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Which assay measurement is either all or none?
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quantal
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Viral genome integrated into cellular DNA
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provirus
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viral genome persists in the nucleas as an extrachromosomal element
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episome
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This is a cell that will support a productive viral infection
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permissive cell
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This is a cell that will not support a productive viral infection, an abortive infection results, cell may be transformed.
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non-permissive cell
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This plaque assay measures the actual amount of infectious units per dilution.
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quantitative assay
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This plaque assay is measured by counting lesions on CAMs of egg embryos.
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pock assay
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What are the three different plaque assays?
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quantitative
pock cell culture |
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What does a Virus-serum neutralization assay do?
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Estimates the amount of antiviral antibodies that can neutralize viral infectivity.
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This modern assay tells you viral specific antigens the body is responding to.
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Western Immunoblot
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What are the two mechanisms of penetration for a virus?
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fushion
receptor mediated endocytosis |
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What two major things happen during the eclipse phase?
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production of viral regulatory enzymes and structural proteins
replication of viral nucleic acid |
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What are two examples of direct viral infection of immune system effector cells?
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lysis of lymphoreticular cells
viral-induced immune cell |
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z
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z
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z
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z
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