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18 Cards in this Set
- Front
- Back
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Defect glycoprotein ,Ib,V ,IX |
Bernard soulier disease |
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Associated with giant plt,abnormal aggregation with ristocetin |
Bernard soulier disease |
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Decrease vWF and glycoprotein Ib |
Von willebrand disease |
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Associated with chromosome 19 ,mark connecting Swizz cheese |
Herniasky-pudlak syndrome |
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Decrease plt dense granule |
Herniasky-pudlak syndrome |
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Chromosome 13 |
Chediak higashi |
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Associated with primary and secondary granules giant lysosomes |
CHS |
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CHS is present in |
Albinism ,abnormal pigment, repeated plt |
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Decrease in number of granules ,small plt |
WAS |
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Triad for recurrent infection,eczema,dec plt |
Was |
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Aggregation pattern response |
Dec aggregation response ADP,collagen,epinephrine Normal response to thrombin |
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Dec atp-adp ratio |
Storage pool disease |
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Deficiency of alpha granules ,large plt |
Gray plt syndrome |
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Lab finding of gray plt syndrome |
Prolong BT Thrombocytopenia ThrombocytopeniaFibrosis of bmLarge plt Fibrosis of bm Large plt |
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Thrombocytopenia |
<100,000/mm3 |
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Due to excessive deposition of platelet aggregation in renal and cerebral vessel |
Thrombotic thrombocytopenic purpura |
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Believed due to vascular wall dysfunction |
TTP |
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TTP is common in |
Woman |
