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10 Cards in this Set
- Front
- Back
List and describe the various autonomic receptors |
2 main types: Cholinergic receptors: binds to ACh. Classified as either Nicotinic or muscarinic. Adrenergic receptors: binds to NE. Classified into 2 categories, as Alpha receptors with subtypes (alpha 1 & beta 1) excitatory or Beta receptors with subtypes (alpha 2 & beta 2) inhibitory. |
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Which divisions are the 2 autonomic receptors found? |
Cholinergic receptors: Nicotinic receptors are located on the cell bodies of BOTH sympathetic and parasympathetic postganglionic neurons. Muscarinic receptors are located on the cells of all parasympathetic neurons/target cells. Adrenergic receptors: Located on sympathetic postganglionic neuron only. |
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What's the difference between cholinergic neurons and receptors VS adrenergic neurons and receptors? |
Cholinergic neurons- spit out ACh, Cholinergic receptors- receive ACh. Adrenergic neurons- spit out NE, Adrenergic receptors- receive NE |
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What's the difference between agonists and antagonists? |
Agonists: bind to specific receptors and activate them. Cholinergic receptors (nicotinic agents & muscarinic agents) Antagonists: bind to specific receptors and prevent them from being activated. Adrenergic receptors. Or (Nicotinic blocking agents and muscarinic blocking agents) |
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What is dual innervation? |
2 neurons, 1 target. Both sympathetic and parasympathetic divisions have 2 neurons to 1 target. |
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Where does the preganglionic neuron go vs the postganglionic neuron? |
Preganglionic neuron goes through the white ramus and Postganglionic neuron goes through the gray ramus. |
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What is the location of the ganglia for the parasympathetic division, vs the sympathetic division? |
Parasympathetic: Terminal/intramural (at or near target organ. Sympathetic: sympathetic chain/a few prevertebral (right in front of vertebrae). |
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What is the target for the parasympathetic vs sympathetic division? |
Parasympathetic: has muscarinic-cholinergic receptors Sympathetic: has beta adrenergic receptors. |
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What is the length of the parasympathetic preganglionic neuron vs the sympathetic preganglionic neuron? Are they myelinated? |
Parasympathetic preganglionic neuron: long and myelinated. Sympathetic preganglionic neuron: short and myelinated. |
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What is the length of the parasympathetic postganglionic neuron vs the sympathetic postganglionic neuron? Are they myelinated? |
Parasympathetic postganglionic neuron: short and unmyelinated. Sympathetic postganglionic neuron: long and unmyelinated. |