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16 Cards in this Set
- Front
- Back
Cerebellum tumor.
Cell origin: undifferentiated embryonal cells. Homer Wright Rosettes, can spread through subarachnoid space/CSF, "frosting on brain," WHO grade IV, common in kids. |
Medulloblastoma
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WHO grade II, found in the walls around ventricles, most common spinal cord glioma, spreads through CSF, perivascular pseudorosettes and ependymal rosettes. Common in kids.
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Ependymoma
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Either primary or secondary (from astrocytoma). WHO grade IV. Most common primary tumor in adults.
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Glioblastoma
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Any tumor from oligodendrocytes or astrocytes
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Glioma
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Intermediate to high- grade non-Hodgkin's lymphomas, B cell type. Periventricular and often multiple. EBV associated with some. Found in elderly and immunocompromised.
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CNS lymphoma
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Vascular tumor seen with Van Hipple - Lindau disease, foamy stromal cells of unknown origin. Usually middle age patients.
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Hemangioblastoma
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Benign epithelial tumor from Rathke's pouch epithelium. Symptoms related to increased ICP: compression of pituitary gland, optic chiasm, 3rd ventricle. Bimodal age distribution: kids ages 5-14, Adults >50.
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Craniopharyngioma
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One type of glioma, preference for white matter, fried egg appearance, calcifications common, delicate capillary beds look like chicken wire, median survival 10 years.
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Oligodendroglioma
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Usually grade I or II, >60% of primary CNS tumors.
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Astrocytoma
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Extra axial, tumor of the schwann cells, usually sensory nerves, can dissect tumor off nerve.
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Schwannoma
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Extra axial, proliferation of schwann cells, fibrobladsts, and perineural cells, intrinsic to nerve.
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Neurofibroblastoma
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Grade I, circumscribed, mural nodule with a cyst, Rosenthal fibers, seen most in cerebellum (also optic nerve and hypothalamus). Common in kids.
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Pilocytic astrocytoma
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Most common CNS cancer in adults. Usually from lung, breast, and melanoma.
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Metastatic carcinoma
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Extra-axial, from arachnoid cap cells, tumor recapitulates normal features of these cells. Whorls, psammoma bodies, three grades (benign, atypical, malignant/anaplastic), usually a single tumor, higher grade increases recurrence rate. More common in females. 20% of primary brain tumors. Can cause seizures, can invade bone.
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Meningioma
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Three most common adult cancers
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Metastatic carcinoma
Glioma (astrocytoma, oligodendroglioma) Meningioma |
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Three most common kid cancers
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Pilocytic astrocytoma
Ependymoma Medulloblastoma |