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67 Cards in this Set
- Front
- Back
The nervous system derives from the |
Ectoderm |
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The endoderm, mesoderm, and ectoderm make up the three layers of the |
Gastrula |
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What’s the order? Oocyte, _______, Blastula, _________ |
Morula, Gastrula |
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Term for formation of the neural tube by the closing of the ectoderm |
Neurulation |
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CNS and heart are the two parts of the body that develop ______ |
Fastest |
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Myelination starts in the ____ trimester |
2nd |
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Human brain general growth: CNS: ____ weeks Fetus formed: 10 weeks _____ ______: 13 weeks |
3-5, primary sulci |
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the inner cell mass of the _________ is the future embryo |
Blastocyst |
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the bilaminar germ disk forms in what week? |
2nd |
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The epiblast and hypoblast are the layers of what? |
Bilaminar germ disk, (epiblast becomes embryo) |
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The trilaminar germ disc forms in what week? |
3rd |
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This is made up of the ectoderm, mesoderm, and endoderm |
Trilaminar germ disk |
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What is the process by which the bilaminar germ disk becomes trilaminar? |
Gastrulation |
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Which layer of the trilaminar germ disc has the notochord? |
Mesoderm (middle) |
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The notochord is responsible for |
Induction |
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________ is cell-cell interaction, where the secretion of one cell affects neighboring cells |
Induction |
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The _____ _______ has to be completely closed, or else it leads to defects |
Neural pore |
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What derives from the neural crest? (Frilly part outside of tube) |
PNS sensory cells |
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What derives from the neural tube? |
CNS Neurons |
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The organizer region does what in the neural tube? |
Induction |
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How do you get two embryos in one system? (Two-headed fish) |
Remove the organizer region from the dorsal part of one embryo, and put it into the ventral part of another embryo |
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T or F: Gradients of the amount of a gene, and variants of a gene, are key to how they function |
TrueT or |
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T or F: The same gene can have different functions at different locations and timesGene |
True |
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Genetic controls are ________ among different animal species |
Conservative |
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What is BMP? If |
Bone morphogenetic protein, (its inhibitors spread from the organizer region of an embryo) |
|
If BMP signaling is inhibited, you get ______ |
neural tissue |
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If BMP signaling is NOT inhibited, you get ___________ tissue. |
Epidermal |
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If the BHLH gene is activated, you get ______ |
neurons |
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If the Notch gene is activated, you get _________ |
Astrocytes (glia) |
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The three vesicle stage of brain development involves what three parts? |
Proencephalon, mescencephalon, rhombencephalon |
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What does the proencephalon become? |
Forebrain (telencephalon and diencephalon) |
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What does the rhombencephalon become? |
Hindbrain (metencephalon, myelencephalon) |
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What is the correct order of the five secondary vesicles? |
(T,D,Ms,Mt,My) |
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the ________ flexure becomes the mesencephalon (brain/spinal cord curve) |
cephalic |
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The cervical flexure becomes the __________ |
rhombencephalon (spinal cord) |
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the ________ flexure becomes the myelencephalon and metencephalon |
pontine |
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Anteroposterior (AP) patterning has to do with which gene? |
Wnt |
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In the _______ part of the neural plate, there is low Wnt activity because Wnt inhibitors are high there |
Anterior |
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In the posterior part of the neural plate there is _____ wnt activity |
High |
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The AP (wnt) gradient works by turning on different TFs. _______ for anterior, and GBX2 for ______ |
OTx2 , posterior |
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What is the name of the longitudinal groove along the neural tube? |
Sulcus limitans |
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Dorsoventral patterning in the spinal cord is controlled by the _________ and ________ |
roofplate and floorplate |
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The dorsal alar plate makes future _______ cells in the spinal cord |
sensory |
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The ventral basal plate makes future _______ cells in the spinal cord |
motor |
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The roofplate and floorplate function like the ________ in that they secrete chemicals in order to induce neuron development |
notochord |
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Sonic hedgehog (shh) is the most important _______ molecule |
Floorplate (motor) |
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What familiar molecule also exists in the roofplate, this time making cells in the dorsal alar plate to be sensory cells?There |
BMP |
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There are many variants of ____ genes, which are responsible for segments, legs, and motor neurons |
Hox |
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What is the name of the longitudinal groove along the neural tube? |
Sulcus limitans |
|
Dorsoventral patterning in the spinal cord is controlled by the _________ and ________ |
roofplate and floorplate |
|
The dorsal alar plate makes future _______ cells in the spinal cord |
sensory |
|
The ventral basal plate makes future _______ cells in the spinal cord |
motor |
|
The roofplate and floorplate function like the ________ in that they secrete chemicals in order to induce neuron development |
notochord |
|
Sonic hedgehog (shh) is the most important _______ molecule |
Floorplate (motor) |
|
What familiar molecule also exists in the roofplate, this time making cells in the dorsal alar plate to be sensory cells?There |
BMP |
|
There are many variants of ____ genes, which are responsible for segments, legs, and motor neurons |
Hox |
|
In AP patterning, _______ is the main inducer and determines what TFs are expressed. Anterior has a high gradient of Pax 6, and posterior has EMX 2. |
FGF 8 |
|
What is the name of the longitudinal groove along the neural tube? |
Sulcus limitans |
|
Dorsoventral patterning in the spinal cord is controlled by the _________ and ________ |
roofplate and floorplate |
|
The dorsal alar plate makes future _______ cells in the spinal cord |
sensory |
|
The ventral basal plate makes future _______ cells in the spinal cord |
motor |
|
The roofplate and floorplate function like the ________ in that they secrete chemicals in order to induce neuron development |
notochord |
|
Sonic hedgehog (shh) is the most important _______ molecule |
Floorplate (motor) |
|
What familiar molecule also exists in the roofplate, this time making cells in the dorsal alar plate to be sensory cells?There |
BMP |
|
There are many variants of ____ genes, which are responsible for segments, legs, and motor neurons |
Hox |
|
In AP patterning, _______ is the main inducer and determines what TFs are expressed. Anterior has a high gradient of Pax 6, and posterior has EMX 2. |
FGF 8 |
|
The anterior part of the forebrain is for _____ and somatosensory, and posterior part is for the auditory and _______ cortices |
motor, visual |