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19 Cards in this Set
- Front
- Back
Zoonotic bacteria
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1. Borrelia burdorferi
2. Francisella tularensis 3. Yersinia pestis 4. Pasteurella multocida 5. Brucella spp. |
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Borrelia burgdorferi: Disease states
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Lyme disease
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Brucella: Disease states
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Undulant fever/Brucellosis.
Temperature slowly rises during day, peaks in the evening, and slowly declines to normal by morning. Accompanied by other systemic symptoms. |
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Brucella: Transmission
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from animal contact (meat worker, farmer, veterinarian) or unpasteurized milk
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Gross mechanism of brucellosis
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1. Penetration of skin (but no buboes or primary skin ulcer), conjunctiva, lungs, GI tract
2. Lymphatic spread 3. Facultative intracellular growth in macrophages, and blood and organ invasion |
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Francisella Tularensis: Disease states (list)
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Tularemia, either:
1. Pneumonic 2. Oculoglandular 3. Ulceroglandular 4. Typhoidal (Don't POUT when you've got tularemia.) |
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Describe Ulceroglandular tularemia
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a. Well-demarcated hole in the skin with a black base
b. Fever and systemic symptoms c. Swollen/red/painful purulent lymph nodes - Similar to plague, but with skin ulcer, and low mortality. |
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Francisella tularensis: Transmission
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Most common: Handling of infected rabbits or from bites of ticks and deer flies - Hundred creatures in total all over US. Mnemonic: Francis the rabbit is playing in the TULips, with a deerfly on one ear and a tick on the other.
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Virulence of Francisella tularensis
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Very. (10 organisms cause disease.)
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Diagnosis of Francisella tularensis
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Clinical picture, PPD-like skin test, and titers of Francisella Ig
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Yersinia pestis: Transmission
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PESTS like rats harbor the disease and fleas are the vector, biting the skin of humans.
Found in campers, hunters, and hikers. Mnemonic: A rat driving a fuel-injected (F1) VW bug (V and W antigens) fleeing (flea-ing) from a macrophage. |
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Fraction 1 (F1) antigen
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Enables Yersinia pesitis to resist destruction after phagocytosis (facultative intracellular) - Mnemonic: A rat driving a fuel-injected (F1) VW bug (V and W antigens) fleeing (flea-ing) from a macrophage.
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V antigen
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Enables Yersinia pesitis to resist destruction after phagocytosis (facultative intracellular)
Mnemonic: A rat driving a fuel-injected (F1) VW bug (V and W antigens) fleeing (flea-ing) from a macrophage. |
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W antigen
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Enables Yersinia pesitis to resist destruction after phagocytosis (facultative intracellular)
Mnemonic: A rat driving a fuel-injected (F1) VW bug (V and W antigens) fleeing (flea-ing) from a macrophage. |
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Yersinia pestis: Presentation in humans
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1. Lymph node (usually inguinal [boubon is Greek for groin]) becomes inflamed (all four signs).
2. Fever, and headache. 3. Blackish discoloration under skin ("Black death") |
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Disease states caused by Yersinia pestis
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Bubonic plague/pneumonic plague
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Pasteurella Multocida: Transmission
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Cat, dog, and animal bites. Also infects birds. Mnemonic: Cat and dog chasing a bird in a "Pasteur".
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T/F: All Zoonotic Gram negative bugs are facultative intracellular.
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False. Pasteurella is not.
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Pasteurella: Treatment
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Do not suture wound after dog or cat bite/scratch. (Best breeding ground for Pasteurella) Treat with penicillin or doxycycline.
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