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16 Cards in this Set
- Front
- Back
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Osteosarcoma
*Mosaic pattern with interspersed osteoid (pink) that is being over produced. *Highly malignant *occurs at age 20 around the knee |
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Giant Cell Tumor
*Arrow points to multi-nucleated osteoclast *Benign but locally aggressive *Commonly occur in Epiphysis of any bone at age 20-40 |
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Lipoma
*Most common benign soft tumor in adults *Clear cell appearance w/ small nuclei pushed off to one side |
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Seborrheic Keratosis
*Circled area shows acanthosis (thickening of epidermis) *Blue arrow points to a horned cyst (aka a keratin pseudocyst) |
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Seborrheic Keratosis
*Black arrow points to a keratin pseudocyst (aka Horned cyst) *Blue shows thick epidermis (acanthosis) |
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Acanthosis of Seborrheic Keratosis
i.e. thick epidermis |
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Taken from a raised skin leison |
Basal Cell Carcinoma
*Nodules of blue basal cells in dermis (arrow) |
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Taken from a raised skin leison |
Basal Cell Carcinoma
*Cells at the periphery of basal tumor nodules in dermis have a palasade "picket-fence" pattern |
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Intradermal Melanocytic Nevus
*Nests of dark nevus cells in dermis (arrow) only and none at the D-E jxn. Intact epidermis |
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Intradermal Melanocytic Nevus
*Black points to sebacous glands *Yellow points to hair follicle |
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Intradermal Melanocytic Nevus
*Nevus cell nests in dermis only with no nests at the D-E jxn. Intact epidermis |
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Bullous Pemphgoid
*Separation of epidermis (red) from dermis (blue) forming a fluid-filled Sub-epidermal bullae *Due to auto-antibody against hemidesmosomes that anchor basalis layer to dermis |
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Taken for a 7mm mole |
Malignant Melanoma
*Malignant melanocytes are polygonal or spindle shaped and grow in sheets (Black arrow) *cuffed by rim of lighter blue lymphocytes (yellow arrow) *Surface is ulcerated (lighter pink section) |
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Taken from dermis of a mole sample |
Malignant Melanoma
*Neoplastic melanocytes are polygonal shaped and have large nucleus w/ prominent nucleoli. *Neural Crest derived |
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Taken from mole |
Malignant Melanoma
*Neoplastic cells involving epidermis with extensions into papillary dermis and leakage of melanocytes into dermis
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Taken from skin sample |
Malignant Melanoma
*Arrow points to melanin that is being over-produced by neoplastic cells in dermis |
