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38 Cards in this Set

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  • Back
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Structures of lower Resp tract

1) trachea


2) brochiole tree


3 alveoli

Conducting part end at .... and resp part start in.....

Terminal bronchiole


Resp bronchiole

What are the four layers of trachea ...

Mucosa


Submucosa


Cartilage layer


Adventitia

Smooth muscle B/T submucusa and cartilage

Which layer has


epithelium & lamina propria ....


serous, mucus glands.....


rings of hyaline cartilage....


C.T with adipocytes.....

Mucusa


Submucusa


Cartilage layer


Adventitia


Muscle found post trachea

trachealis

Runs through vagus

Type of mucusa epith

Pseudostratified ciliated columnar

Cells of lining epith????

Ciliated columnar


Goblet


stem


Brush


granule

Go back see cack

What type of cell is —


mucociliary escalator ...


receptor cells....


Neuroendocrine......


Ciliated columnar


Brush cells


granule

Cell have microvilli and Contact with nerve endings .....

Brush cells

Cell secrete hormones

granule

Cells of Lamina propria

lymphocytes


plasma cells


eosinophils


mast cells


fibroblasts

Has this cells because it has blood vessels

Submucusa gland:-


Secretion.....


Surround by ....

1– ( mucin, lysozyme, Ig A , lactoferrin )


2- Myoepithelial

Bronchial tree ...

بلستر

What’s the changes as we move down through bronchial tree

decreased in — diameter, cartilage, glands, goblet cells, height of epith cells


increase in — smooth muscle cells and elastic tissue

How to differentiate B/t resp and term bronchiole?

— Terminal bronchiole :-


2 layer of smooth muscle


folded mucosa


— Resp bronchiole:-


continue with Alveolar duct


1 layer of smooth


Structural differences B/T bronchi and trachea

bronchi has :-


- pulmonary artery branches in Adventitia


- smaller hyaline


- Additional layer of smooth muscle

Part has no Cartilage, Glands , Gobletcells but has thick smooth muscle

bronchioles

Epithelial cell of bronchiole

simple cuboidal

Type of cell found in bronchioles ??

clara cells


occasional brush ( عريضه)


granule



Type of cell found in bronchioles ??

clara cells


occasional brush ( عريضه)


granule



spasm of smooth muscle in bronchial cause difficulty in .....

expiration

In case if asthma

Type of cell found in bronchioles ??

clara cells


occasional brush ( عريضه)


granule



spasm of smooth muscle in bronchial cause difficulty in .....

expiration

Clara cell secrete

surfactant lipoprotein


Clara cell protein (CC16)

surfactant lipoprotein
Clara cell protein (CC16)

CC16 serves as,,,

Marker for lung injury


decreased in bronchoalveolar secretion and increased in serum


Type of epith on proximal and distal resp bronchiole

Proximal — cuboidal+ clara


Distal— squamous

Different B/T type 1,2 alveoli

Type1 :-


squamous + gaseous exchange


Type 2:-


cuboidal + Secretes surfactant + Brush cells


Type of epith on proximal and distal resp bronchiole

Proximal — cuboidal+ clara


Distal— squamous

Different B/T type 1,2 alveoli

Type1 :-


squamous + gaseous exchange


Type 2:-


cuboidal + Secretes surfactant + Brush cells


Cells ، fibers of intra alveolar septal


Cells — Fibro- macro- mast


Fibers— Reticular - elastic

Layers of Air-blood barrier

Surfactant


Epith


Basal lamina


Endoth



thick part of this barrier has C.T)

MQ in septum called.... but in alveolar spaces......

alveolar macrophages


dust cells

MQ in septum called.... but in alveolar spaces......

alveolar macrophages


dust cells

What does heart failure cells mean?

MQ phagocyte erythrocytes escape from capillary in patient with congestive heart failure

Cystic fibrosis caused by mutation in (CTFR) gene which results in

- ⬇️ Cl- channel protein


- Exocrine glands secrete mucus

Cystic fibrosis caused by mutation in (CTFR) gene which results in

- ⬇️ Cl- channel protein


- Exocrine glands secrete mucus

Different B/T Pneumonia and Pulmonary edema ???

Pulmonary edema — fluid in interstitial space and air spaces


Pneumonia— air spaces filled with inflam cell

antitrypsin deficiency in smokers lead to...

Emphysema