Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
3 Components of athersclerotic plaque
|
1. Cell - SMC, Macrophages, T cells
2. ECM - Collagen, elastic fibers, proteoglycans 3. Lipid - Intra and extra-cellular |
|
Atherosclerotic sites (vessels)
|
Order of descending frequency:
Abdominal Aorta Coronary artrey Popliteal artery Internal carotids |
|
Components of fibrous cap
|
SMC
dense collagen |
|
Necrotic center is composed of what?
|
Cellular debris
cholesterol crystals foam cells |
|
What are the consequences of atherosclerosis
|
MI
CVA Aortic aneurysm peripheral vascular disease |
|
Hyaline Arteriosclerosis
|
Homogeneous hyaline thickening of the walls.
Basement membrane leaks plasma components across vascular endothelium. Excessive ECM by SMC. |
|
Hyperplastic Arteriosclerosis
|
"Onion-skin", Concentric, Laminated thickening of the wall.
SMC proliferation and duplicated basement membrane. Characteristic of malignant hypertension. (diastolic > 120mmHg) Necrotizing arteriolitis (Fibrinoid deposits and wall necrosis) |