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37 Cards in this Set
- Front
- Back
What is the difference in treatment in Seminomas and Nonseminomatous Germ-cell tumors (NSGCT)?
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Seminomas are RADIOSENTITIVE
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What is the most common site of Metastases of Seminomas?
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Para-aortic lymph nodes
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Seminoma
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A 30 year old man noticed painless enlargement of the left testicle and after 3 months decided to consult his family physician. The physician palpated the testes and found that the left testicles is enlarged and irregularly nodular and firm. He referred him to a urologist. AFP and hCG were normal
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Seminoma
-tumor cells are arranged in lobules surrounded by fibrous strands and infiltrated with lymphocytes |
What is this?
How do you know? |
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Intratubular Testicular Germ Cell Neoplasia = carcinoma in situ
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What is this?
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Teratoma
- keratin pearls - glands -neural tissue |
What cancer is this?
How do you know? |
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Choriocarcinoma cells
- bulky masses with Hemorrhage and necrosis |
What germ cell tumor is this?
What is the characteristic microscopic feature? |
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Yolk Sac
Schiller-Duval Bodies AFP |
What Germ Cell Tumor?
How do you know? What do they secrete (tumor marker)? |
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Leydig cell tumor
90% are usually benign *androgens secreted from Leydig tumor cells caused precocious puberty |
8 year old boy bragged to his friend that his penis has grown during the summer vacation and that he has pubic hair. Had elevated blood androgens.
-What testicular cancer? -Is it most likely to be benign or malignant? |
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Leydig Cell tumor
- Reinke crystalloids - round nuclei with eosinophilic cytoplasm |
What type of tumor is this?
What are the characteristics of the histology? |
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Yolk Sac Tumor
- 2 year old - Schiller-duval bodies |
A 2 year old had a tumor mass. This is the histology of the mass.
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Yolk Sac tumor
-Schiller-Duval bodies |
What testicular tumor?
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Mumps
- Meningitis - Orchitis = Seminiferous tubule with inflammation - Parotitis |
A 3 year old boy developed fever, swelling on both sides of his face. The left testicle was enlarged and sensitive to touching.
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A 70 year old man noticed that his right testis is enlarged and slightly painful and sensitive to palpation
What is the MOST LIKELY tumor? |
Metastases from a different site
- Malignant Lymphoma |
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1. Male infertility
2. FSH (b/c loss inhibin made from Sertoli cells) 3. loss of Seminiferous tubules and decreased Testosterone 4. Orchitis, ischemia, toxic injury |
1. What is this condition?
2. What would be elevated? 3. What would cause a decreased sperm count? 4. What are possible causes? |
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1. Leygid Cell tumor
2. Secrete hormones - Androgen = macrogenitosomia - Estrogen = Gynecomastia |
A 50 year old man noticed that his breast have enlarged during the last 6 months. He also noticed slight scrotal discomfort. Physical examination revealed an irregularly enlarge slightly nodular left testicle.
1. What is the tumor? 2. What is the cause of the symptoms? |
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Syphillis = Treponema pallidum
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What would be the cause of these 2 symptoms?
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Systemic Vasculitis involving small blood vessels in many organs:
1. Recurrent ulcers -mouth -penis/scrotum that are painful -vulva/vagina 2. Skin purpura/ulcerations 3. Arthritis |
Behcet Syndrome
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Neisseria gonorrhoea
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A 28 year old man came back from a weekend in Baltimore and noticed a yellow discharge from his penis, associated with burning pain
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N. gonorhoea inside neutrophils
- diplococci |
Specimen taken from a urethral discharge
What is the agent? |
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What are the 3 most common microbes causing Urethritis?
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1. Chlamydia trachomatis
2. N. gonorrhoea 3. Ureaplasma urealyticum |
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Non-infectios Urethritis of unknown etiology preceded by GI or GU infections
Clinical Triad: - Urethritis - Conjunctivitis - Arthritis of weight carrying joints |
Reiter Syndrome
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Fibromatosis of the penis in adults
- curvature of erect penis - pain on erection - painful intercourse |
Peyronie disease
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What part of the penis has fibrosis in Peyronie disease?
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Tunica Albuginea
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Indwelling Catheter
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A 60 year old man underwent coronary artery bypass surgery. In the first urine that he voided on his own he noticed blood.
What is this most likely due to? |
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Transitional Cell Carcinoma of the bladder
Smoking |
What type of cancer is this?
What is the greatest risk factor? |
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Benign Prostatic Hyperplasia
- median lobe of prostate has formed a valve - trabeculae are on the bladder wall |
Describe all the findings you see here
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Benign prostatic hyperplasia
- trabeculae - stones - diverticulum |
What is the cause of all this?
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Prostate cancer
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What is this?
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Prostate Cancer
Adenocarcinoma |
What cancer is this?
What histological cancer is it? |
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Benign Prostatic Hyperplasia
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A 62 year old man had a yearly check-up. The only abnormality was elevation of PSA in the blood. Biopsy showed this. What is the diagnosis?
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Embryonal Carcinoma Cells in NSGCT
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What is this?
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Mumps
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What likely caused this?
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Rectum
Urinary Bladder Prostate |
This is metastatic testicular cancer. From where did it most likely originate?
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Metastatic Testicular Adenocarcinoma = came from somewhere else
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What kind of tumor is this?
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Papillary Trasitional cell of the Urinary Bladder
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What kind of tumor is this?
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