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41 Cards in this Set

  • Front
  • Back

Occlusion of the small penetrating arteries deep within the brain

Lacunar Stroke

WATERSHED STROKE

Ischemic stroke that occurs at the junction of distal field of two non anastomosing arterial system

ACA syndrome

Contralateral hemiparesis of lower limbs ,urinary incontinence and apraxia

MCA syndrome

Contralateral hemiparesis and hemisensory loss in the face and arms.Aphasia can occur depending upon the side

Cerebellar Infarction

Type of vertebral artery syndrome.Incoordination, ataxia, and dysarthia

Locked -in syndrome

Type of vertebral artey syndrome. Infarct of upper central pons.quadriphlegia with preserved consciousness

PCA occlusion

Hemianopia and macular sparing

Amyloid Angiopathy

Accumulation of abnormal proteins in cerebral arteries.Leads to narrowing and ischemia,then weakness and ICH.Definitive diagnosis needs brain tissue sample

Transthoracic Echocardiogram

Done on all stroke patients.Good for showing abnormalities such as dyskinetic wall segment

Brain Requirements

20percent of body's oxygen


15percent of body's cardiac output

Cerebral blood flow

Normal-50-56ml/100g/min


moderate ischemia(the penumbra) 20-30ml/100g/min


severe ischemia and cell death 0-10ml/100g/min

Large vessel occlusion

Embolic:developed elsewhere and travel to blood vessel in the brain

Small vessel occlusion

Thrombotic : caused by a clot that develops in the vessel of the brain

Cerebral Cortex

Gray matter on the outermost section of the cerebrum and cerebellum


divided into 4lobes -frontal,parietal,occipital and temporal

Frontal lobe

motor, behavioral expression,Motor sensory maps

Parietal lobe

sensation,optic radiations carrying sensory input from the eyes ,language centers typically left side of brain

Language Centers

Broca's: Production/expressive


Wernicke's: Comprehension/receptive

Occipital Lobe

Vision and interpretation of visual sensory signals

Dysarthia

slurred speech ,reflecting poor motor control of yhe muscles associated with speech and language

Temporal lobe

coding visual memory and processing aufitory and visual sensory input and language comprehension

Basal ganglia

a group of nuclei serving as the coordinating center for several nerve tract including coordinating muscle movement

Glubos pallidus

a key component of the basal ganglia instrumental in control of voluntary muscle movement

Limbic system

a group of nuclei and cortical structures that encode memory and regulate autonomic nervous system and endocrine function in response to emotional situations

Hypothalamus

coordinates autonomic nervous system with endocrine function,control body temperature circadian rhythmn and body water/osmolality

Amygdala

Plays a crucial role in the management of stress,rage ,anxiety.Center for memory and emotions

Cingulate gyrus

develop emotions and encode memory

Diencephalon

between the brainstem and cerebellum

Thalamus

The brain's sensory switchboard located on top of the brainstem.It directs messages to the sensory receiving areas in the cortex and trabsmits replies to the cerebellum and medulla

tPA dosing

0.9mh/kg



10percent administered over 1minute


remainder over an hour


Maximum dose:90mg

Non enhanced CT

parenchymal brain imaging-


computer processed xrays to yeild cross sectional images

MR spectroscopy

a technique that investigates metabolic changes in the brain

FOUR score

Eye reaction, motor function, brain stem reflexes and respiratory pattern

Barthel index

self care and mobility scalr


100 is normal


the lower the score , the higher the disability and dependency

Neurologic Assessment: Ischemic stroke

Full NIHSS Should be performed before and after tPA


15min x 2hrs


30minx 6hrs


1hrx 24 hrsa

Cerebrospinal fluid is produced at a rate of

0.3-0.4ml/min

A lacunar infarct is indicative of an event

in small artery

The risk factot for spontaneous carotid dissection

Connective tissue diases

MRI diffusion weihted imaging

the most sensitive and specific imagingvtechnique for demonstrating acute infarction

anaphylaxis

a rare but potential complication to tPA administration

Trauma

the most common cause of vertebral dissection

Characteristic of basilar stroke

coma, quadriparesis, ataxia, CN dysfunction, "locked -in syndrome"